ArticlePloS one2024
Hypertension subtypes at high altitude in Peru: Analysis of the Demographic and Family Health Survey 2016-2019.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Higher Prevalence of Cognitive Impairment in Residents of High-Altitude Regions.Oxygen (Basel, Switzerland) · 2026Article
- Development and Temporal Validation of a Multinomial Prediction Model for Phenotypes of Undiagnosed Hypertension in Peru: A Population-Based Study.Medical sciences (Basel, Switzerland) · 2026Article
- Fruit and Vegetable Consumption and Its Public Health Implications for Hypertension Among Peruvian Aged 15 Years and Older: Evidence from the 2022-2023 Demographic and Health Survey.Healthcare (Basel, Switzerland) · 2026Article
- The association between altitude and cerebral small vessel disease burden in the Tibetan population: a cross-sectional study.Scientific reports · 2025Article
- Short-term trends in hypertension and high cardiovascular risk at high altitude in Peru.Frontiers in public health · 2025Article
- [Current Status and Prospects of Research on Altitude-Related Hypertension].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Review
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of hypertension in Peru has increased over the years. Approximately one third of the Peruvian population lives at high altitudes. This population presents particular physiological, genetic and environmental characteristics that could be related to the prevalence of hypertension and its subtypes.
objectiveTo assess the association between altitude and hypertension in the Peruvian population through an analysis of a nationally representative survey.
methodsWe conducted a cross-sectional analysis of the Demographic and Family Health Survey for the period 2016-2019. We included 122,336 individuals aged 18 years and older. Hypertension was defined according to the JNC-7 guidelines. High-altitude location was defined as a residential cluster located above 2,500 meters above sea level. We utilized generalized linear models from the Poisson family with a log-link function to assess the magnitude of the association between high altitude and hypertension. Additionally, we employed multinomial regression models to analyze the association between high altitude and subtypes of hypertension, including isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and systolic-diastolic hypertension (SDH).
resultsIn the adjusted Poisson regression model, we found that the prevalence of hypertension among participants living at high altitudes was lower compared to those living at low altitudes (aPR: 0.89; 95% CI: 0.86-0.93). In the adjusted multinomial regression model, we observed a lower prevalence rate of ISH among participants residing at high altitudes (aRPR: 0.68; 95% CI: 0.61-0.73) and a higher prevalence rate of IDH among participants residing at high altitudes (aRPR: 1.60; 95% CI: 1.32-1.94).
conclusionsResidents at high altitudes in Peru have a lower prevalence rate of ISH and a higher prevalence rate of IDH compared to those living at low altitudes. Further studies are needed to determine the influence of other biological, environmental, and healthcare access factors on this relationship.
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