Evidence map›Paper›PMID 38607943›Full record

ArticleVascular medicine (London, England)2024

Urinary vanin-1 as a novel biomarker for survival in peripheral artery disease.

Bernhard Zierfuss, Anna Karlinger, Marija Bojic, Renate Koppensteiner, Gerit-Holger Schernthaner, Clemens Höbaus

Open access · hybridAbstract read
In one paragraph

Article in Vascular medicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Synthesis of Potent Vanin-1 Inhibitors Labelled With Carbon-14 and Deuterium.Journal of labelled compounds & radiopharmaceuticals · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bernhard ZierfussMedicine II, Division of Angiology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3225-9063
Anna KarlingerMedicine II, Division of Angiology, Medical University of Vienna, Vienna, Austria.
Marija Bojic1st Medical Department, Hanusch Hospital, Vienna, Austria.
Renate KoppensteinerMedicine II, Division of Angiology, Medical University of Vienna, Vienna, Austria.
Gerit-Holger SchernthanerMedicine II, Division of Angiology, Medical University of Vienna, Vienna, Austria.
Clemens HöbausMedicine II, Division of Angiology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-9704-1452
Medical University of Vienna · ATHanusch Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease is associated with increased rates of incidence, morbidity, and mortality in lower-extremity peripheral artery disease (PAD). No specific marker for a functional risk assessment of kidney disease in PAD is known, especially at the early stages. Thus, we speculated that urinary vanin-1 (uVNN1), a marker of oxidative stress even in early kidney injury, could further stratify outcome assessment in patients with PAD.

methodsPatients with stable PAD (

resultsuVNN1/Cr was associated with a urine albumin-creatinine ratio (UACR) (

conclusionsuVNN1/Cr showed an independent association with both all-cause and cardiovascular mortality in patients with PAD and was associated with early kidney disease. Thus, uVNN1 could be a useful marker for risk stratification of kidney disease in PAD.

Indexed as

BiomarkersPeripheral Arterial DiseasePredictive Value of TestsAgedAged, 80 and overAlbuminuriaAmidohydrolasesAustriaCause of DeathCreatinineEnzyme-Linked Immunosorbent AssayFemaleGlomerular Filtration RateGPI-Linked ProteinsHumansKidneyAmidohydrolasesBiomarkersCreatinineGPI-Linked Proteinspantetheinasechronic kidney diseasefibrosisinflammationmortalityperipheral artery disease (PAD)urinary vanin-1, biomarkers

Identifiers

PMID38607943
PMCPMC11323407
OpenAlexW4394769185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.