Evidence map›Paper›PMID 38607913›Full record

ArticleCell reports2024

ptx3a

Jisheng Sun, Elizabeth A Peterson, Xin Chen, Jinhu Wang

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jisheng SunCardiology Division, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Elizabeth A PetersonCardiology Division, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Xin ChenCardiology Division, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Jinhu WangCardiology Division, School of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address: jinhu.wang@emory.edu.
Emory University · US

Funding

T cell triggering events and hypertensionP01HL095070 · NHLBI · EMORY UNIVERSITY · PI GRIENDLING, KATHY K · 2009 to 2019
$20.5M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Vasiliki Michopoulos · 2018 to 2026
$12.2M
Research Trainng in Academic CardiologyT32HL007745 · NHLBI · EMORY UNIVERSITY · PI TAYLOR, WILLIAM ROBERT · 1994 to 2023
$10.6M
Characterization of hapln1a positive cells during zebrafish heart regenerationR01HL142762 · NHLBI · EMORY UNIVERSITY · PI Jinhu Wang · 2019 to 2026
$2.6M
NHLBI NIH HHS P01 HL095070NHLBI NIH HHS R01 HL142762NHLBI NIH HHS T32 HL007745NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

Macrophages conduct critical roles in heart repair, but the niche required to nurture and anchor them is poorly studied. Here, we investigated the macrophage niche in the regenerating heart. We analyzed cell-cell interactions through published single-cell RNA sequencing datasets and identified a strong interaction between fibroblast/epicardial (Fb/Epi) cells and macrophages. We further visualized the association of macrophages with Fb/Epi cells and the blockage of macrophage response without Fb/Epi cells in the regenerating zebrafish heart. Moreover, we found that ptx3a

Indexed as

FibroblastsHeartMacrophagesRegenerationZebrafishAnimalsC-Reactive ProteinHeart InjuriesPentraxinsPericardiumSerum Amyloid P-ComponentZebrafish ProteinsC-Reactive ProteinPentraxinsSerum Amyloid P-ComponentZebrafish ProteinsCP: ImmunologyCP: Stem cell researchcsf1aepicardiumheartmacrophageptx3aregenerationzebrafish

Identifiers

PMID38607913
PMCPMC11092985
OpenAlexW4394711488

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.