Evidence map›Paper›PMID 38607603›Full record

ArticleBiotechnology letters2024

Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium.

Emils Bolmanis, Oskars Grigs, Elina Didrihsone, Maris Senkovs, Vizma Nikolajeva

Abstract read
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In one paragraph

Article in Biotechnology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Spore production optimization of a biofertilizer based on Bacillus cabrialesii HB7 for enhancing plant growth under saline stress.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emils BolmanisLaboratory of Bioengineering, Latvian State Institute of Wood Chemistry, Dzerbenes Street 27, Riga, 1006, Latvia.ORCID http://orcid.org/0000-0002-5087-2179
Oskars GrigsLaboratory of Bioengineering, Latvian State Institute of Wood Chemistry, Dzerbenes Street 27, Riga, 1006, Latvia. oskars.grigs@kki.lv.ORCID http://orcid.org/0000-0002-1848-4176
Elina DidrihsoneLaboratory of Bioengineering, Latvian State Institute of Wood Chemistry, Dzerbenes Street 27, Riga, 1006, Latvia.
Maris SenkovsBioefekts Ltd., Livzemes Street 30, Salaspils, 2169, Latvia.ORCID http://orcid.org/0000-0001-6773-5667
Vizma NikolajevaBioefekts Ltd., Livzemes Street 30, Salaspils, 2169, Latvia.ORCID http://orcid.org/0000-0002-5823-7292

Funding

European Regional Development Fund 1.1.1.1/19/A/150Latvian State Institute of Wood Chemistry 07-23 (SubtScale)
6 · The paper itself

Abstract

objectivesBacillus subtilis is a plant growth promoting bacterium (PGPB) that acts as a microbial fertilizer and biocontrol agent, providing benefits such as boosting crop productivity and improving nutrient content. It is able to produce secondary metabolites and endospores simultaneously, enhancing its ability to survive in unfavorable conditions and eliminate competing microorganisms. Optimizing cultivation methods to produce B. subtilis MSCL 897 spores on an industrial scale, requires a suitable medium, typically made from food industry by-products, and optimal temperature and pH levels to achieve high vegetative cell and spore densities with maximum productivity.

resultsThis research demonstrates successful pilot-scale (100 L bioreactor) production of a biocontrol agent B. subtilis with good spore yields (1.5 × 10

conclusionAn economically-feasible process for B. subtilis-based biocontrol agent production was successfully developed at the pilot scale.

Indexed as

Bacillus subtilisBiomassBioreactorsCulture MediaSpores, BacterialAntifungal AgentsPilot ProjectsAntifungal AgentsCulture MediaAntifungal metaboliteBacillus subtilisBiofungicideLow-cost mediumPilot-scale bioreactorSpore production

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.