Evidence map›Paper›PMID 38607503›Full record

ArticleInflammopharmacology2024

Artemisia herba-alba: antioxidant capacity and efficacy in preventing chronic arthritis in vivo.

Hicham Wahnou, Martin Ndayambaje, Zaynab Ouadghiri, Salma Benayad, Hicham Elattar, Oumaima Chgari, Abdallah Naya, Younes Zaid, Mounia Oudghiri

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Plants (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hicham WahnouLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.ORCID http://orcid.org/0000-0003-1375-4111
Martin NdayambajeLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.ORCID http://orcid.org/0009-0000-9695-4930
Zaynab OuadghiriLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.ORCID http://orcid.org/0000-0002-8816-3001
Salma BenayadLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.
Hicham ElattarAnnasr Pathology Center, 24000, El Jadida, Morocco.
Oumaima ChgariLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.
Abdallah NayaLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.
Younes ZaidLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco.ORCID http://orcid.org/0000-0001-8750-9106
Mounia OudghiriLaboratory of Immunology and Biodiversity, Faculty of Sciences Ain Chock, Hassan II University, Maarif, B.P2693, Casablanca, Morocco. mounia.oudghiri@univh2c.ma.ORCID http://orcid.org/0000-0002-5815-1579

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arthritis is a debilitating condition impacting the quality of life for millions worldwide, characterized by pain and inflammation. Understanding the mechanisms of arthritis and developing effective treatments are crucial. This study investigated the hydroethanolic extract of Artemisia herba-alba for its protective potential against arthritis hallmarks, oxidative stress, and lipid peroxidation in vitro. It also assessed its in vivo anti-arthritic activity. The phytochemical analysis identified various compounds within the extract, with high concentrations of polyphenols and flavonoids. These compounds are associated with numerous health benefits, making A. herba-alba a potential source of valuable phytochemicals. A. herba-alba demonstrated a notable effect in body weight loss, paw edema, and arthritic severity. Histopathological examination revealed structural improvements in bone and muscle tissues, emphasizing its therapeutic potential in managing chronic arthritis. Furthermore, while these findings are promising, further studies are necessary to delve deeper into the mechanisms underlying the observed hematological changes and to gain a more comprehensive understanding of the in vivo results. This research sets the stage for continued exploration, ultimately aiming to unlock the full potential of A. herba-alba in addressing chronic arthritis and enhancing the lives of those affected by this condition.

Indexed as

AntioxidantsArtemisiaArthritis, ExperimentalOxidative StressPlant ExtractsAnimalsArthritisChronic DiseaseEdemaFlavonoidsLipid PeroxidationMaleMicePhytochemicalsRatsAntioxidantsFlavonoidsPhytochemicalsPlant ExtractsAnti-inflammatoryAntioxidantArtemisia herba-albaCarrageenanChronic arthritisFreund adjuvant

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.