ArticleIntensive care medicine experimental2024
Oxygenation and ventilation during prolonged experimental cardiopulmonary resuscitation with either continuous or 30:2 compression-to-ventilation ratios together with 10 cmH
Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- The use of supplemental oxygen during cardiopulmonary resuscitation - a systematic review of the literature.Resuscitation plus · 2026Article
- Chest compression synchronized ventilation during prolonged experimental cardiopulmonary resuscitation improves oxygenation but may cause pneumothoraces.Resuscitation plus · 2025Article
- Detecting pneumothorax during cardiopulmonary resuscitation: The potential of defibrillator measured transthoracic impedance.Resuscitation plus · 2024Article
- A multimodal characterization of cardiopulmonary resuscitation-associated lung edema.Intensive care medicine experimental · 2024Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn refractory out-of-hospital cardiac arrest, the patient is commonly transported to hospital with mechanical continuous chest compressions (CCC). Limited data are available on the optimal ventilation strategy. Accordingly, we compared arterial oxygenation and haemodynamics during manual asynchronous continuous ventilation and compressions with a 30:2 compression-to-ventilation ratio together with the use of 10 cmH
methodsIntubated and anaesthetized landrace pigs with electrically induced ventricular fibrillation were left untreated for 5 min (n = 31, weight ca. 55 kg), after which they were randomized to either the CCC group or the 30:2 group with the the LUCAS® 2 piston device and bag-valve ventilation with 100% oxygen targeting a tidal volume of 8 ml/kg with a PEEP of 10 cmH
resultsThe arterial blood values (median + interquartile range) at the 30-min time point were as follows: PaO
conclusionsThe 30:2 and CCC protocols with a PEEP of 10 cmH
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