Evidence map›Paper›PMID 38606869›Full record

ReviewThe world journal of men's health2025

The Role of Autophagy in Erectile Dysfunction.

Changjing Wu, Yang Xiong, Fudong Fu, Fuxun Zhang, Feng Qin, Jiuhong Yuan

Open access · diamondAbstract readReview
In one paragraph

Review in The world journal of men's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Changjing Wu *Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-8684-1825
Yang Xiong *Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-3901-2394
Fudong FuInstitutes for Systems Genetics, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-8773-694X
Fuxun ZhangAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-0113-0395
Feng QinAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-9521-7146
Jiuhong YuanAndrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-0991-1463
Sichuan University · CN

Funding

Natural Science Foundation of China 82071639Sichuan Science and Technology Program 2022YFS0134
6 · The paper itself

Abstract

Autophagy is a conservative lysosome-dependent material catabolic pathway, and exists in all eukaryotic cells. Autophagy controls cell quality and survival by eliminating intracellular dysfunction substances, and plays an important role in various pathophysiology processes. Erectile dysfunction (ED) is a common male disease. It is resulted from a variety of causes and pathologies, such as diabetes, hypertension, hyperlipidemia, aging, spinal cord injury, or cavernous nerve injury caused by radical prostatectomy, and others. In the past decade, autophagy has begun to be investigated in ED. Subsequently, an increasing number of studies have revealed the regulation of autophagy contributes to the recovery of ED, and which is mainly involved in improving endothelial function, smooth muscle cell apoptosis, penile fibrosis, and corpus cavernosum nerve injury. Therefore, in this review, we aim to summarize the possible role of autophagy in ED from a cellular perspective, and we look forward to providing a new idea for the pathogenesis investigation and clinical treatment of ED in the future.

Indexed as

ApoptosisAutophagyEndothelial cellsErectile dysfunctionFibrosisSmooth muscle

Identifiers

PMID38606869
PMCPMC11704175
OpenAlexW4394762937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.