Evidence map›Paper›PMID 38606619›Full record

ReviewBioscience reports2024

Me31B: a key repressor in germline regulation and beyond.

Ming Gao

Open access · goldAbstract readReview
In one paragraph

Review in Bioscience reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Science advances · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ming GaoBiology Department, Indiana University Northwest, Gary, IN, U.S.A.
Indiana University Northwest · US

Funding

Determining the Role of Me31B Protein in Germ Cell DevelopmentR15HD092925 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI GAO, MING · 2018 to 2023
$875k
NICHD NIH HHS R15 HD092925
6 · The paper itself

Abstract

Maternally Expressed at 31B (Me31B), an evolutionarily conserved ATP-dependent RNA helicase, plays an important role in the development of the germline across diverse animal species. Its cellular functionality has been posited as a translational repressor, participating in various RNA metabolism pathways to intricately regulate the spatiotemporal expression of RNAs. Despite its evident significance, the precise role and mechanistic underpinnings of Me31B remain insufficiently understood. This article endeavors to comprehensively review historic and recent research on Me31B, distill the major findings, discern generalizable patterns in Me31B's functions across different research contexts, and provide insights into its fundamental role and mechanism of action. The primary focus of this article centers on elucidating the role of Drosophila Me31B within the germline, while concurrently delving into pertinent research on its orthologs within other species and cellular systems.

Indexed as

Drosophila ProteinsGerm CellsAnimalsDrosophilaDrosophila melanogasterGene Expression Regulation, DevelopmentalHumansRNA HelicasesDrosophila ProteinsRNA HelicasesGerm granulesGermlineMe31BNeuronal granulesRibonucleoprotein (RNP)RNA helicase

Identifiers

PMID38606619
PMCPMC11065648
OpenAlexW4394764929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.