Evidence map›Paper›PMID 38606347›Full record

ArticleJACC. Advances2024

Preoperative Hemodynamics Impact the Benefit of Fenestration on Fontan Postoperative Length of Stay.

Garick D Hill, Danny T Y Wu, M Eric Ferguson, Saul Flores, Salil Ginde, Kevin D Hill, Michael Johansen, Jane W Newburger, Zhiqian Gao, James F Cnota

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Unplanned Readmissions due to Pleural Effusion Following the Fontan Operation.World journal for pediatric & congenital heart surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Garick D HillDivision of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Danny T Y WuDivision of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
M Eric FergusonChildren's Healthcare of Atlanta, Emory University, Atlanta, Georgia, USA.
Saul FloresSection of Critical Care Medicine and Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Salil GindeDepartment of Medicine and Pediatrics, Children's Wisconsin, Milwaukee, Wisconsin, USA.
Kevin D HillDepartment of Pediatrics, Duke Pediatric and Adult Congenital Heart Center, Duke Children's Hospital, Durham, North Carolina, USA.
Michael JohansenDivision of Cardiology, Riley Children's Hospital at Indiana University Health, Indianapolis, Indiana, USA.
Jane W NewburgerDepartment of Cardiology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Zhiqian GaoThe Heart Institute Research Core, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
James F CnotaDivision of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Funding

MIS-C Program: Data Coordinating Center for the Pediatric Heart Network MIS-C ProgramU24HL135691 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2017 to 2024
$37.9M
NHLBI NIH HHS L40 HL148932NHLBI NIH HHS U24 HL135691
6 · The paper itself

Abstract

backgroundUtilization of Fontan fenestration varies considerably by center.

objectivesUsing a multicenter Pediatric Heart Network dataset linking surgical and preoperative hemodynamic variables, the authors evaluated factors associated with use of Fontan fenestration and the impact of fenestration on post-Fontan length of stay (LOS).

methodsPatients 2 to 6 years old at Fontan surgery from 2010 to 2020 with catheterization<1 year prior were included. Factors associated with fenestration were evaluated using multivariable logistic regression adjusting for key covariates. Restrictive cubic spline analysis was used to evaluate potential cut-points for hemodynamic variables associated with longer postoperative LOS stratified by fenestration with multivariable linear regression to evaluate the magnitude of effect.

resultsFenestration was used in 465 of 702 patients (66.2%). Placement of a fenestration was associated with center (range 27%-93% use,

conclusionsThere is wide center variability in use of Fontan fenestration that is not explained by preoperative hemodynamics. Fenestration is independently associated with shorter LOS, and those with mPAP ≥13 mm Hg at pre-Fontan catheterization benefit the most. We propose this threshold as minimal criteria for fenestration.

Indexed as

Glenn pressurehypoplastic left heart syndromesingle ventricle

Identifiers

PMID38606347
PMCPMC11008224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.