Evidence map›Paper›PMID 38606182›Full record

ArticleFrontiers in pharmacology2024

Optimizing fluconazole-embedded transfersomal gel for enhanced antifungal activity and compatibility studies.

Zhiqiang Cheng, Ujjwala Kandekar, Xiaoshi Ma, Vishal Bhabad, Ashlesha Pandit, Liming Liu, Jiping Luo, Neha Munot, Trushal Chorage, Abhinandan Patil and 2 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhiqiang ChengZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Ujjwala KandekarDepartment of Pharmaceutics, JSPM's Rajarshi Shahu College of Pharmacy and Research, Pune, Maharashtra, India.
Xiaoshi MaDepartment of Pathology, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
Vishal BhabadDepartment of Pharmaceutics, JSPM's Rajarshi Shahu College of Pharmacy and Research, Pune, Maharashtra, India.
Ashlesha PanditDepartment of Pharmaceutics, JSPM's Rajarshi Shahu College of Pharmacy and Research, Pune, Maharashtra, India.
Liming LiuDepartment of Pathology, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
Jiping LuoDepartment of Pathology, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, China.
Neha MunotDepartment of Pharmaceutics, Rajmata Jijau Shikashan Prasarak Mandal College of Pharmacy, Pune, Maharashtra, India.
Trushal ChorageDepartment of Pharmacognosy, JSPM's Charak College of Pharmacy and Research, Pune, Maharashtra, India.
Abhinandan PatilDepartment of Pharmaceutics, D. Y. Patil Education Society, Kolhapur, Maharashtra, India.
Sandip PatilDepartment of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.
Liang TaoZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal infections are of major concern all over the globe, and fluconazole is the most prevalently used drug to treat it. The goal of this research work was to formulate a fluconazole-embedded transfersomal gel for the treatment of fungal infections. A compatibility study between fluconazole and soya lecithin was performed by differential scanning calorimetry (DSC). Transfersomes were formulated by a thin-film hydration technique using soya lecithin and Span 80. A central composite design was adopted to prepare different formulations. Soya lecithin and Span 80 were chosen as independent variables, and the effect of these variables was studied on

Indexed as

ex-vivo studiesfluconazoletopical applicationtransfersomal geltransfersomes

Identifiers

PMID38606182
PMCPMC11007155

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.