Evidence map›Paper›PMID 38606081›Full record

ReviewFrontiers in chemistry2024

Microelement strontium and human health: comprehensive analysis of the role in inflammation and non-communicable diseases (NCDs).

Xin Ru, Lida Yang, Guohui Shen, Kunzhen Wang, Zihan Xu, Wenbo Bian, Wenqi Zhu, Yanzhi Guo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Efficacy of Strontium Cream in Alleviating Pruritus in Hidradenitis Suppurativa.The Journal of clinical and aesthetic dermatology · 2025
    Article
  12. Article
  13. Review
  14. Harnessing strontium in regenerative dentistry: progress and perspectives.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Xin Ru *Institute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing, China.
Lida YangCollege of Nursing, Mudanjiang Medical University, Mudanjiang, China.
Guohui ShenInstitute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing, China.
Kunzhen WangInstitute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing, China.
Zihan XuInstitute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing, China.
Wenbo BianZibo Agricultural Science Research Institute, Shandong, China.
Wenqi ZhuAgricultural Information Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Yanzhi GuoChinese Academy of Agricultural Sciences, Beijing, China.
Ministry of Agriculture and Rural Affairs · CNAgricultural Information Institute · CNChinese Academy of Agricultural Sciences · CNMudanjiang Medical University · CNRural Development Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strontium (Sr), a trace element with a long history and a significant presence in the Earth's crust, plays a critical yet often overlooked role in various biological processes affecting human health. This comprehensive review explores the multifaceted implications of Sr, especially in the context of non-communicable diseases (NCDs) such as cardiovascular diseases, osteoporosis, hypertension, and diabetes mellitus. Sr is predominantly acquired through diet and water and has shown promise as a clinical marker for calcium absorption studies. It contributes to the mitigation of several NCDs by inhibiting oxidative stress, showcasing antioxidant properties, and suppressing inflammatory cytokines. The review delves deep into the mechanisms through which Sr interacts with human physiology, emphasizing its uptake, metabolism, and potential to prevent chronic conditions. Despite its apparent benefits in managing bone fractures, hypertension, and diabetes, current research on Sr's role in human health is not exhaustive. The review underscores the need for more comprehensive studies to solidify Sr's beneficial associations and address the gaps in understanding Sr intake and its optimal levels for human health.

Indexed as

human healthinflammationmicroelementnon-communicable diseasesstrontium

Identifiers

PMID38606081
PMCPMC11007224
OpenAlexW4393276533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.