Evidence map›Paper›PMID 38605900›Full record

ArticleRSC advances2024

Immunomodulatory zymosan/ι-carrageenan/ agarose hydrogel for targeting M2 to M1 macrophages (antitumoral).

Geetha Venkatachalam, Jayant Giri, Saurav Mallik, Gandarvakottai Senthilkumar Arumugam, Manavalan Arulmani, Vimal Kumar Dewangan, Mukesh Doble, Zhongming Zhao

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Immunomodulatory Effects of the Tobacco Defensin NaD1.Antibiotics (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Geetha VenkatachalamBioengineering and Drug Design Lab, Department of Biotechnology, Indian Institute of Technology Madras 600036 Chennai Tamilnadu India.
Jayant GiriDepartment of Mechanical Engineering, Yeshwantrao Chavan College of Engineering Nagpur India.
Saurav MallikDepartment of Pharmacology and Toxicology, University of Arizona Tucson AZ USA.
Gandarvakottai Senthilkumar ArumugamBioengineering and Drug Design Lab, Department of Biotechnology, Indian Institute of Technology Madras 600036 Chennai Tamilnadu India.
Manavalan ArulmaniDepartment of Cariology, Saveetha Dental College, SIMATS 600077 Chennai Tamilnadu India mukeshdoble.sdc@saveetha.com mukeshd@iitm.ac.in.
Vimal Kumar DewanganDepartment of Metallurgical and Materials Engineering, Indian Institute of Technology Madras 600036 Chennai India.
Mukesh DobleDepartment of Cariology, Saveetha Dental College, SIMATS 600077 Chennai Tamilnadu India mukeshdoble.sdc@saveetha.com mukeshd@iitm.ac.in.ORCID https://orcid.org/0000-0002-7533-3024
Zhongming ZhaoMcWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston Houston TX USA Zhongming.zhao@uth.tmc.edu.
Indian Institute of Technology Madras · INSaveetha University · INThe University of Texas Health Science Center at Houston · USUniversity of Arizona · USYashwantrao Chavan Maharashtra Open University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have been performed on the immunomodulatory effects of yeast β-(1,3) glucan, but there is no proper evaluation of the thermal and immunomodulating properties of zymosan (ZM). Thermogravimetry analysis indicated a 54% weight loss of ZM at 270 °C. Circular dichroism showed absorption peaks in the region of 250 to 400 nm, suggesting a helical coil β-sheet configuration. XRD showed a broad peak at 2

Identifiers

PMID38605900
PMCPMC11008189
OpenAlexW4394730028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.