Evidence map›Paper›PMID 38605598›Full record

ArticleNucleus (Austin, Tex.)2024

A lineage-specific protein network at the trypanosome nuclear envelope.

Erin R Butterfield, Samson O Obado, Simon R Scutts, Wenzhu Zhang, Brian T Chait, Michael P Rout, Mark C Field

Open access · goldAbstract read
In one paragraph

Article in Nucleus (Austin, Tex.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Enhanced Detection of Homology Using Artificial Intelligence in Euglenids.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Erin R ButterfieldSchool of Life Sciences, University of Dundee, Dundee, UK.ORCID 0009-0005-1811-6233
Samson O ObadoLaboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA.ORCID 0000-0003-3161-0218
Simon R ScuttsDepartment of Pathology, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2670-3682
Wenzhu ZhangLaboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY, USA.ORCID 0009-0001-3154-871X
Brian T ChaitLaboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, NY, USA.ORCID 0000-0003-3524-557X
Michael P RoutLaboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA.ORCID 0000-0003-2010-706X
Mark C FieldSchool of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0002-4866-2885
Rockefeller University · USUniversity of Dundee · GBUniversity of Cambridge · GB

Funding

TR&D Project 4. The Imaging Stage: Multiscale Spatiotemporal Modeling of Macromolecular Systems in Cellular NeighborhoodsP41GM109824 · NIGMS · ROCKEFELLER UNIVERSITY · PI ROUT, MICHAEL P · 2014 to 2023
$18.8M
Structure-Function Mapping of the Nuclear Pore Complex-RenewalR01GM112108 · NIGMS · ROCKEFELLER UNIVERSITY · PI JOHN D. AITCHISON, MICHAEL P ROUT · 2015 to 2026
$9.1M
Molecular and Functional Dissection of Distinct mRNA Export PathwaysR01AI140429 · NIAID · ROCKEFELLER UNIVERSITY · PI OBADO, SAMSON, ROUT, MICHAEL P · 2019 to 2022
$1.5M
The development of tools for proteomic analysis in trypanosomesR21AI096069 · NIAID · ROCKEFELLER UNIVERSITY · PI ROUT, MICHAEL P · 2011 to 2012
$466k
NIAID NIH HHS R01 AI140429NIAID NIH HHS R21 AI096069NIGMS NIH HHS P41 GM109824NIGMS NIH HHS R01 GM112108Wellcome Trust
6 · The paper itself

Abstract

The nuclear envelope (NE) separates translation and transcription and is the location of multiple functions, including chromatin organization and nucleocytoplasmic transport. The molecular basis for many of these functions have diverged between eukaryotic lineages.

Indexed as

Nuclear EnvelopeTrypanosomaHumansNuclear PoreNuclear Pore Complex ProteinsSaccharomyces cerevisiaeNuclear Pore Complex ProteinsAlphaFoldcomparative genomicsmolecular evolutionnuclear laminanuclear pore complexNucleus

Identifiers

PMID38605598
PMCPMC11018031
OpenAlexW4394760787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.