ArticleGenome biology2024
Scoary2: rapid association of phenotypic multi-omics data with microbial pan-genomes.
Article in Genome biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Comparative Genomic Analysis of Clonal Variants of aMicroorganisms · 2026Article
- A community-based One Health approach to the pandemic dynamics ofAntimicrobial agents and chemotherapy · 2026Article
- High-precision binary trait association on phylogenetic trees.Microbial genomics · 2026Article
- Convergent evolution of ST2 and ST164 mediates dissemination of the blaAnnals of clinical microbiology and antimicrobials · 2026Article
- Exploring clonality ofMicrobiology spectrum · 2026Article
- Advances, opportunities, and challenges in microbial community construction: from environmental remediation to biomanufacturing.Archives of microbiology · 2026Review
- Genomic comparison and phenotypic characterization ofmSystems · 2026Article
- Phage-meropenem synergy against OXA-48-producing Klebsiella pneumoniae clinical isolates.npj antimicrobials and resistance · 2026Article
- Pseudoalteromonas is a symbiont of marine invertebrates that exhibits broad patterns of phylosymbiosis.The ISME journal · 2026Article
- Genomic dissection of the clonal background and global dissemination of hypervirulent Klebsiella pneumoniae CG23-KL57 lineage.Nature communications · 2026Article
- Towards a holistic epidemiology ofFrontiers in bioinformatics · 2026Article
- Comparative genomic analyses provide new insights into phylogenetic and functional diversification in genusFrontiers in microbiology · 2026Article
- Discovery and genomics of HISME communications · 2026Article
- The pangenome: a statistical model, not a fixed biological property.Bioinformatics advances · 2026Review
- Pangenome-GWAS analysis ofCanadian journal of microbiology · 2026Article
- Genomic Insights intoPathogens (Basel, Switzerland) · 2025Article
- Bacterial Systematic Genetics and Integrated Multi-Omics: Beyond Static Genomics Toward Predictive Models.International journal of molecular sciences · 2025Review
- Article
- Bacterial genome-wide association studies: exploring the genetic variation underlying bacterial phenotypes.Applied and environmental microbiology · 2025Review
- Article
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Authors and funding
10 authors.
Funding
Abstract
Unraveling bacterial gene function drives progress in various areas, such as food production, pharmacology, and ecology. While omics technologies capture high-dimensional phenotypic data, linking them to genomic data is challenging, leaving 40-60% of bacterial genes undescribed. To address this bottleneck, we introduce Scoary2, an ultra-fast microbial genome-wide association studies (mGWAS) software. With its data exploration app and improved performance, Scoary2 is the first tool to enable the study of large phenotypic datasets using mGWAS. As proof of concept, we explore the metabolome of yogurts, each produced with a different Propionibacterium reichii strain and discover two genes affecting carnitine metabolism.
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Registered trials
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