Evidence map›Paper›PMID 38605179›Full record

ArticleActa pharmacologica Sinica2024

The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.

Gu-Fang Zhang, Kai-Lian Zhu, Qi Li, Yue Zhang, John L Waddington, Xiang-Dong Du, Xue-Chu Zhen

Open access · greenAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gu-Fang Zhang *Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Kai-Lian Zhu *Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Qi LiJiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Yue ZhangSuzhou Medical College, Soochow University, Suzhou, 215123, China.
John L WaddingtonJiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Xiang-Dong DuDepartment of Psychiatry, The Affiliated Guangji Hospital of Soochow University, Suzhou, 215003, China. xiangdong-du@163.com.
Xue-Chu ZhenJiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China. zhenxuechu@suda.edu.cn.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SCH23390 is a widely used D

Indexed as

BenzazepinesReceptors, Dopamine D1Receptors, sigmaSigma-1 ReceptorAllosteric RegulationAnimalsDopamine AntagonistsHEK293 CellsHumansMaleMiceMice, Inbred C57BLBenzazepinesDopamine AntagonistsReceptors, Dopamine D1Receptors, sigmaSCH 23390Sigma-1 Receptorallosteric modulationGSK3βpharmacological actionsSCH23390Sigma-1 receptor

Identifiers

PMID38605179
PMCPMC11272936
OpenAlexW4394716463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.