Evidence map›Paper›PMID 38605177›Full record

ArticleCell research2024

Structural basis for human Ca

Jian Huang, Xiao Fan, Xueqin Jin, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan

Open access · hybridAbstract read
In one paragraph

Article in Cell research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Hyperpolarization Modulation of the T-Type hCaAngewandte Chemie (International ed. in English) · 2025
    Article
  12. Calcium channels as pharmacological targets for cancer therapy.Clinical and experimental medicine · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore region.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Jian Huang *Department of Molecular Biology, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-6861-0425
Xiao Fan *Department of Molecular Biology, Princeton University, Princeton, NJ, USA. fanxiao0606@gmail.com.
Xueqin Jin *Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Chen LyuBeijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Qinmeng GuoBeijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Tao LiuBeijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Jiaofeng ChenBeijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
Amaël DavakanIGF, Université de Montpellier, CNRS, INSERM, LabEx 'Ion Channel Science and Therapeutics', Montpellier, France.
Philippe LoryIGF, Université de Montpellier, CNRS, INSERM, LabEx 'Ion Channel Science and Therapeutics', Montpellier, France.
Nieng YanBeijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. nyan@tsinghua.edu.cn.ORCID 0000-0003-4829-7416
Center for Life Sciences · CNCentre National de la Recherche Scientifique · FRPrinceton University · USKing Center · US

Funding

Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) 23307-G0001-10013397-101Human Frontier Science Program (HFSP) LT000754National Natural Science Foundation of China (National Science Foundation of China) 32330052
6 · The paper itself

Abstract

The Ca

Indexed as

Calcium Channel BlockersCalcium Channels, T-TypeCryoelectron MicroscopyBinding SitesHEK293 CellsHumansModels, MolecularProtein BindingCACNA1H protein, humanCalcium Channel BlockersCalcium Channels, T-Type

Identifiers

PMID38605177
PMCPMC11143251
OpenAlexW4394726783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.