Evidence map›Paper›PMID 38605012›Full record

ArticleNature communications2024

Multiscale architecture design of 3D printed biodegradable Zn-based porous scaffolds for immunomodulatory osteogenesis.

Shuang Li, Hongtao Yang, Xinhua Qu, Yu Qin, Aobo Liu, Guo Bao, He Huang, Chaoyang Sun, Jiabao Dai, Junlong Tan and 8 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 92 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Shuang Li *School of Engineering Medicine, School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China.
Hongtao Yang *School of Engineering Medicine, School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China. yang276070@buaa.edu.cn.ORCID http://orcid.org/0000-0002-0495-1554
Xinhua Qu *Department of Bone and Joint Surgery, Department of Orthopedics, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 200001, Shanghai, China.
Yu QinSchool of Materials Science and Engineering, Peking University, 100871, Beijing, China.
Aobo LiuDepartment of Mechanical Engineering, Tsinghua University, 100084, Beijing, China.
Guo BaoDepartment of Reproduction and Physiology National Research Institute for Family Planning, 100081, Beijing, China.
He HuangSchool of Materials Science and Engineering, Zhengzhou University, 450003, Zhengzhou, China.
Chaoyang SunSchool of Engineering Medicine, School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China.
Jiabao DaiDepartment of Mechanical Engineering, Tsinghua University, 100084, Beijing, China.
Junlong TanSchool of Engineering Medicine, School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China.ORCID http://orcid.org/0000-0003-2802-4795
Jiahui ShiSchool of Materials Science and Engineering, Peking University, 100871, Beijing, China.
Yan GuanCollege of Chemistry and Molecular Engineering, Peking University, 100871, Beijing, China.
Wei PanCollege of Chemistry and Molecular Engineering, Peking University, 100871, Beijing, China.
Xuenan GuSchool of Engineering Medicine, School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China.
Bo JiaDepartment of Mechanical Engineering, Tsinghua University, 100084, Beijing, China.ORCID http://orcid.org/0000-0002-4809-6457
Peng WenDepartment of Mechanical Engineering, Tsinghua University, 100084, Beijing, China. wenpeng@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-5656-1988
Xiaogang WangSchool of Engineering Medicine, School of Biological Science and Medical Engineering, Beihang University, 100191, Beijing, China. xiaogangwang@buaa.edu.cn.ORCID http://orcid.org/0000-0001-9798-834X
Yufeng ZhengSchool of Materials Science and Engineering, Peking University, 100871, Beijing, China. yfzheng@pku.edu.cn.ORCID http://orcid.org/0000-0002-7402-9979
Peking University · CNBeihang University · CNTsinghua University · CNShanghai Jiao Tong University · CNZhengzhou University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 52101282National Natural Science Foundation of China (National Science Foundation of China) 52175274National Natural Science Foundation of China (National Science Foundation of China) 82350003, 92049201National Natural Science Foundation of China (National Science Foundation of China) U22A20121, 5231101024, 51931001
6 · The paper itself

Abstract

Reconciling the dilemma between rapid degradation and overdose toxicity is challenging in biodegradable materials when shifting from bulk to porous materials. Here, we achieve significant bone ingrowth into Zn-based porous scaffolds with 90% porosity via osteoinmunomodulation. At microscale, an alloy incorporating 0.8 wt% Li is employed to create a eutectoid lamellar structure featuring the LiZn

Indexed as

OsteogenesisTissue ScaffoldsPorosityPrinting, Three-DimensionalZincZinc

Identifiers

PMID38605012
PMCPMC11009309
OpenAlexW4394718054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.