Evidence map›Paper›PMID 38604778›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Optogenetic Determination of Dynamic and Cell-Type-Specific Inhibitory Reversal Potentials.

Richard J Burman, Tara Diviney, Alexandru Călin, Gemma Gothard, Jean-Sébastien M Jouhanneau, James F A Poulet, Arjune Sen, Colin J Akerman

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Direct energy consumption by inhibitory GABAFrontiers in neuroscience · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Richard J BurmanDepartment of Pharmacology, University of Oxford, Oxford OX1 3QT, United Kingdom.
Tara DivineyDepartment of Pharmacology, University of Oxford, Oxford OX1 3QT, United Kingdom.
Alexandru CălinDepartment of Pharmacology, University of Oxford, Oxford OX1 3QT, United Kingdom.
Gemma GothardDepartment of Pharmacology, University of Oxford, Oxford OX1 3QT, United Kingdom.
Jean-Sébastien M JouhanneauMax-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin 13125, Germany.
James F A PouletMax-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin 13125, Germany.
Arjune SenOxford Epilepsy Research Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, United Kingdom.
Colin J AkermanDepartment of Pharmacology, University of Oxford, Oxford OX1 3QT, United Kingdom colin.akerman@pharm.ox.ac.uk.ORCID 0000-0001-6844-4984
University of Oxford · GBMax Delbrück Center · DEOxford Research Group · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The reversal potential refers to the membrane potential at which the net current flow through a channel reverses direction. The reversal potential is determined by transmembrane ion gradients and, in turn, determines how the channel's activity will affect the membrane potential. Traditional investigation into the reversal potential of inhibitory ligand-gated ion channels (E

Indexed as

Membrane PotentialsOptogeneticsAnimalsFemaleLigand-Gated Ion ChannelsMaleMiceMice, Inbred C57BLMice, TransgenicNeural InhibitionNeuronsReceptors, GABA-ALigand-Gated Ion ChannelsReceptors, GABA-Aequilibrium potentialion dynamicsneuronal subtypesoptogeneticssynaptic inhibition

Identifiers

PMID38604778
PMCPMC11097265
OpenAlexW4394727939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.