Evidence map›Paper›PMID 38604762›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

PET Quantification of [

John L O'Donnell, Anil Kumar Soda, Hao Jiang, Scott A Norris, Baijayanta Maiti, Morvarid Karimi, Meghan C Campbell, Stephen M Moerlein, Zhude Tu, Joel S Perlmutter

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Assessment of noninvasive quantification of [European journal of nuclear medicine and molecular imaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

John L O'DonnellNeurology, Washington University in Saint Louis, St. Louis, Missouri; jodonn@wustl.edu.
Anil Kumar SodaRadiology, Washington University in Saint Louis, St. Louis, Missouri.
Hao JiangRadiology, Washington University in Saint Louis, St. Louis, Missouri.
Scott A NorrisNeurology, Washington University in Saint Louis, St. Louis, Missouri.
Baijayanta MaitiNeurology, Washington University in Saint Louis, St. Louis, Missouri.
Morvarid KarimiNeurology, Washington University in Saint Louis, St. Louis, Missouri.
Meghan C CampbellNeurology, Washington University in Saint Louis, St. Louis, Missouri.
Stephen M MoerleinRadiology, Washington University in Saint Louis, St. Louis, Missouri.
Zhude TuRadiology, Washington University in Saint Louis, St. Louis, Missouri.
Joel S PerlmutterNeurology, Washington University in Saint Louis, St. Louis, Missouri.
Washington University in St. Louis · US

Funding

Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI RICHARD Justin PERRIN · 2020 to 2026
$28.7M
PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
Parkinson Disease Clinical Subtypes: Validation, Clinical Utility, and Biological CorrelatesR01NS097437 · NINDS · WASHINGTON UNIVERSITY · PI MEGHAN C CAMPBELL · 2017 to 2026
$4.1M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
The Role of Striatal Cholinergic Interneurons in DystoniaR01NS124789 · NINDS · WASHINGTON UNIVERSITY · PI Scott Allen Norris · 2022 to 2026
$3.0M
Precision-Mapping Functional Connectivity in Parkinson's DiseaseR01NS124738 · NINDS · WASHINGTON UNIVERSITY · PI MEGHAN C CAMPBELL, Caterina Gratton · 2023 to 2026
$2.4M
Cerebellar cholinergic connections as a biomarker of dementia and gait impairment in Parkinson diseaseK23NS125107 · NINDS · WASHINGTON UNIVERSITY · PI Baijayanta Maiti · 2022 to 2026
$916k
DEVELOPMENT OF VESICULAR ACETYLCHOLINE TRANSPORTER IMAGING AGENTS FOR PETR21NS061025 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2009 to 2010
$628k
NIA NIH HHS P30 AG066444NINDS NIH HHS K23 NS125107NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS097437NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS107281NINDS NIH HHS R01 NS124738NINDS NIH HHS R01 NS124789NINDS NIH HHS R21 NS061025
6 · The paper itself

Abstract

Molecular imaging of brain vesicular acetylcholine transporter provides a biomarker to explore cholinergic systems in humans. We aimed to characterize the distribution of, and optimize methods to quantify, the vesicular acetylcholine transporter-specific tracer (-)-(1-(8-(2-[

Indexed as

BrainPiperidinesPositron-Emission TomographyAdultAgedAged, 80 and overAgingFemaleHumansMaleMiddle AgedRadiopharmaceuticalsReproducibility of ResultsVesicular Acetylcholine Transport ProteinsYoung AdultPiperidinesRadiopharmaceuticalsVesicular Acetylcholine Transport ProteinsacetylcholinebraincholinergichumanPET

Identifiers

PMID38604762
PMCPMC11149597
OpenAlexW4394728029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.