Evidence map›Paper›PMID 38603649›Full record

ArticleJCO precision oncology2024

Henry de Traux de Wardin, Josephine K Dermawan, Fabio Vanoli, Samuel C Jiang, Samuel Singer, Ping Chi, William Tap, Leonard H Wexler, Cristina R Antonescu

Open access · hybridAbstract read
In one paragraph

Article in JCO precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Henry de Traux de WardinDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0009-0000-0615-8982
Josephine K DermawanRobert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.ORCID 0000-0002-1139-2914
Fabio VanoliDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-1260-8078
Samuel C JiangDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Samuel SingerDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Ping ChiDepartment of Medicine, Sarcoma Service, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-0159-5531
William TapDepartment of Medicine, Sarcoma Service, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-7779-2796
Leonard H WexlerDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0003-0724-8263
Cristina R AntonescuDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-9717-8205
Memorial Sloan Kettering Cancer Center · USCleveland Clinic · USUniversité Libre de Bruxelles · BE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Targeting Oncogenic Pathways in Genetically Complex SarcomasP50CA217694 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI William D. Tap · 2018 to 2026
$21.5M
Understanding and targeting MAPK pathway activation in NF1-deficient malignant peripheral nerve sheath tumor (MPNST)U01CA252048 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CHI, PING · 2021 to 2025
$3.1M
Harnessing double stranded-RNA (dsRNA)-response and anti-tumor effect in PRC2-inactivated cancerR01CA280657 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Ping Chi · 2023 to 2026
$2.9M
Phase II Study of ASTX727 in Patients with PRC2 loss Malignant Peripheral Nerve Sheath Tumor (MPNST)R01FD007544 · FDA · SLOAN-KETTERING INST CAN RESEARCH · PI CHI, PING · 2022 to 2025
$1.6M
FDA HHS R01 FD007544NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA217694NCI NIH HHS R01 CA280657NCI NIH HHS U01 CA252048
6 · The paper itself

Abstract

purposeAlterations of the

methodsWe investigated the clinicopathologic and molecular landscape of a cohort of 22

resultsAmong the RMS group, all except one were ERMS, with a median age of 17 years while for MTT the mean age was 39 years. Three MTTs were misdiagnosed as ERMS, having clinical impact in one. The most frequent coexisting alteration in ERMS was

conclusionPatients with NF1-mutant ERMS lacking

Indexed as

Neurofibromatosis 1RhabdomyosarcomaAdolescentAdultHumansNeurofibrosarcomaPhenotype

Identifiers

PMID38603649
PMCPMC11161258
OpenAlexW4394711039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.