Evidence map›Paper›PMID 38603565›Full record

ReviewAnnual review of genomics and human genetics2024

Causes and Consequences of Varying Transposable Element Activity: An Evolutionary Perspective.

Andrea J Betancourt, Kevin H-C Wei, Yuheng Huang, Yuh Chwen G Lee

Abstract readReview
In one paragraph

Review in Annual review of genomics and human genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Transposon Ecology and the Octopus Genome.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. The Transformation and Protein Expression of the Edible MushroomJournal of fungi (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. From the genome's perspective: Bearing somatic retrotransposition to leverage the regulatory potential of L1 RNAs.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea J BetancourtInstitute of Infection, Veterinary, and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Kevin H-C WeiDepartment of Zoology, University of British Columbia, Vancouver, British Columbia, Canada.
Yuheng HuangDepartment of Ecology and Evolutionary Biology, University of California, Irvine, California, USA.
Yuh Chwen G LeeCenter for Complex Biological Systems, University of California, Irvine, California, USA; email: grylee@uci.edu.

Funding

How transposable elements drive genome evolution through epigenetic mechanismsR35GM142494 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Grace Yuh Chwen Lee · 2021 to 2026
$2.5M
NIGMS NIH HHS R35 GM142494
6 · The paper itself

Abstract

Transposable elements (TEs) are genomic parasites found in nearly all eukaryotes, including humans. This evolutionary success of TEs is due to their replicative activity, involving insertion into new genomic locations. TE activity varies at multiple levels, from between taxa to within individuals. The rapidly accumulating evidence of the influence of TE activity on human health, as well as the rapid growth of new tools to study it, motivated an evaluation of what we know about TE activity thus far. Here, we discuss why TE activity varies, and the consequences of this variation, from an evolutionary perspective. By studying TE activity in nonhuman organisms in the context of evolutionary theories, we can shed light on the factors that affect TE activity. While the consequences of TE activity are usually deleterious, some have lasting evolutionary impacts by conferring benefits on the host or affecting other evolutionary processes.

Indexed as

DNA Transposable ElementsEvolution, MolecularAnimalsHumansDNA Transposable Elementsarms raceevolutionpopulation geneticstransposable elementstransposition

Identifiers

PMID38603565
PMCPMC12105613

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.