Evidence map›Paper›PMID 38603247›Full record

ReviewJournal of generic medicines2022

Repurposing Molnupiravir as a new opportunity to treat COVID-19.

Sahithi Paruchuri, Koushik Yetukuri, RamaRao Nadendla

Open access · greenAbstract readReview
In one paragraph

Review in Journal of generic medicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sahithi ParuchuriDepartment of Pharmaceutical Regulatory Affairs, Chalapathi Institute of Pharmaceutical Sciences (Autonomous), Guntur, India.ORCID https://orcid.org/0000-0002-3488-6861
Koushik YetukuriDepartment of Pharmaceutical Regulatory Affairs, Chalapathi Institute of Pharmaceutical Sciences (Autonomous), Guntur, India.
RamaRao NadendlaDepartment of Pharmaceutical Regulatory Affairs, Chalapathi Institute of Pharmaceutical Sciences (Autonomous), Guntur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the emergence of new and re-emerging viral diseases, scientists have been working to produce new medications with novel targets and pathways. The discovery of safe and efficacious antiviral medicines is critical due to the constant introduction of new virus types and short lifetime of protection. Since the outbreak, there have been significant efforts to repurpose existing and licensed medications for rapid human testing and possible emergency use authorizations. The exploration of surviving medications for new restorative motives is known as drug repurposing. It is a successful, rapid, and highly reliable alternative to traditional drug methods. COVID-19 is being treated using a number of repurposed and new medicines. Molnupiravir is a repurposed Covid-19 medicine that was specifically developed to cure influenza and is used to treat mild to moderately ill Covid-19 patients with high risk of becoming seriously ill. The importance of medication repurposing, as well as the regulatory procedure for repurposed pharmaceuticals and Emergency Use Authorization in the United States, are summarized in this article.

Indexed as

Covid-19Drug repurposingemergency use authorizationMolnupiravirUnited States

Identifiers

PMID38603247
PMCPMC9357751
OpenAlexW4289933490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.