Evidence map›Paper›PMID 38602473›Full record

ArticleJournal of the American Chemical Society2024

DNA Damage Accelerates G-Quadruplex Folding in a Duplex-G-Quadruplex-Duplex Context.

Aaron M Fleming, Brandon Leonel Guerra Castañaza Jenkins, Bethany A Buck, Cynthia J Burrows

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aaron M FlemingDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.ORCID 0000-0002-2000-0310
Brandon Leonel Guerra Castañaza JenkinsDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.ORCID 0000-0003-3936-9879
Bethany A BuckDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.
Cynthia J BurrowsDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.ORCID 0000-0001-7253-8529
University of Utah · US

Funding

Pd-Catalyzed Olefin Functionalization Reactions for Organic SynthesisR01GM063540 · NIGMS · UNIVERSITY OF UTAH · PI SIGMAN, MATTHEW S · 2002 to 2019
$5.3M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR017539 · NCRR · UNIVERSITY OF UTAH · PI PUGMIRE, RONALD J · 2003 to 2003
$3.8M
Chemical Modifications in Regulatory Regions of DNA and RNAR35GM145237 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Cynthia J Burrows · 2022 to 2026
$2.3M
A 500MHz NMR Spectrometer with AutomationS10OD025241 · OD · UNIVERSITY OF UTAH · PI FLYNN, PETER F · 2018 to 2018
$600k
NCRR NIH HHS C06 RR017539NIGMS NIH HHS R01 GM063540NIGMS NIH HHS R35 GM145237NIH HHS S10 OD025241
6 · The paper itself

Abstract

Molecular details for the impact of DNA damage on folding of potential G-quadruplex sequences (PQSs) to noncanonical DNA structures involved in gene regulation are poorly understood. Here, the effects of DNA base damage and strand breaks on PQS folding kinetics were studied in the context of the

Identifiers

PMID38602473
PMCPMC11046481
OpenAlexW4394727437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.