Evidence map›Paper›PMID 38602081›Full record

ReviewExpert reviews in molecular medicine2024

Trauma diagnostic-related target proteins and their detection techniques.

YiLiu Wei, Xiaohan Ren, Zhitao Yuan, Jie Hong, Tao Wang, Weizhi Chen, Yuqing Xu, Jinwang Ding, Jun Lin, Wenqian Jiang and 2 more

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Expert reviews in molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07774338 (Early Admission Serum Soluble Receptor for Advanced Glycation End Products), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07774338 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Early Admission Serum Soluble Receptor for Advanced Glycation End Products (sRAGE), Club Cell Protein-16 (CC16), and Syndecan-1 as Independent Predictors of Acute Respiratory Distress Syndrome and In-Hospital Mortality Following Severe Isolated Chest Trauma: A Prospective Cohort Study.

TypeobservationalSponsorAssiut UniversityRan2026 to 2028Enrolled85ConditionsAcute Respiratory Distress Syndrome, Chest TraumaArmsNo intervention - observational study
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

YiLiu WeiDepartment of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.
Xiaohan RenInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
Zhitao YuanInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
Jie HongDepartment of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.
Tao WangInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
Weizhi ChenDepartment of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.
Yuqing XuInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
Jinwang DingInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
Jun LinInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.
Wenqian JiangInstitute of Applied Genomics, Fuzhou University, No. 2 Xueyuan Road, 350108 Fuzhou, China.ORCID 0000-0001-8738-9896
Peng ZhangInstitute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 200127 Shanghai, China.ORCID 0000-0002-0896-6411
Qiaoyi WuDepartment of Trauma Center & Emergency Surgery, The First Affiliated Hospital of Fujian Medical University, 350004 Fuzhou, China.ORCID 0000-0003-2960-9760
Fuzhou University · CNFujian Medical University · CNShanghai Jiao Tong University · CN

Funding

Fujian Provincial Health Technology Project 2023CXA018Fujian Provincial Major Health Research Project 2022ZD01001Fujian Provincial Science and Technology Plan Project 2022Y4003Fuzhou Health science and technology plan soft science research project 2022-S-WR4Fuzhou Science and Technology Project 2021S263Fuzhou Science and Technology Project 2022S005Fuzhou University Testing Fund of precious apparatus 2024T021Joint Funds for the Innovation of Science and Technology, Fujian ProvinceMajor Research Projects for Young and Middle-aged Researchers of Fujian Provincial Health Commission 2021ZQNZD001Natural Science Foundation of Fujian Province 2022J01521Young and middle-aged talent research project of Fuzhou city 2022-S-RC
6 · The paper itself

Abstract

Trauma is a significant health issue that not only leads to immediate death in many cases but also causes severe complications, such as sepsis, thrombosis, haemorrhage, acute respiratory distress syndrome and traumatic brain injury, among trauma patients. Target protein identification technology is a vital technique in the field of biomedical research, enabling the study of biomolecular interactions, drug discovery and disease treatment. It plays a crucial role in identifying key protein targets associated with specific diseases or biological processes, facilitating further research, drug design and the development of treatment strategies. The application of target protein technology in biomarker detection enables the timely identification of newly emerging infections and complications in trauma patients, facilitating expeditious medical interventions and leading to reduced post-trauma mortality rates and improved patient prognoses. This review provides an overview of the current applications of target protein identification technology in trauma-related complications and provides a brief overview of the current target protein identification technology, with the aim of reducing post-trauma mortality, improving diagnostic efficiency and prognostic outcomes for patients.

Indexed as

Brain Injuries, TraumaticHemorrhageHumansbiomarkersmass spectrometrytarget protein identificationtraumatrauma-related complications

Identifiers

PMID38602081
PMCPMC11062145
OpenAlexW4394720193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.