Evidence map›Paper›PMID 38601952›Full record

ArticleDevelopmental psychobiology2024

Maternal Childhood Adversity and Infant Epigenetic Aging: Moderation by Restless Sleep During Pregnancy.

David W Sosnowski, Darlynn M Rojo-Wissar, Gang Peng, Stephanie H Parade, Katherine Sharkey, Cathrine Hoyo, Susan K Murphy, Raquel G Hernandez, Sara B Johnson

Open access · bronzeAbstract read
In one paragraph

Article in Developmental psychobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Quantification of Epigenetic Aging in Public Health.Annual review of public health · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

David W SosnowskiDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health.ORCID 0000-0003-0007-7027
Darlynn M Rojo-WissarDepartment of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University.ORCID 0000-0001-7353-1353
Gang PengDepartment of Medical & Molecular Genetics, Indiana University School of Medicine.ORCID 0000-0003-0307-9351
Stephanie H ParadeDepartment of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University.ORCID 0000-0003-0978-0886
Katherine SharkeyDepartment of Medicine, The Warren Alpert Medical School of Brown University.ORCID 0000-0003-1743-0704
Cathrine HoyoDepartment of Biological Sciences, Center for Human Health and the Environment North Carolina State University.
Susan K MurphyDepartment of Obstetrics and Gynecology, Duke University School of Medicine.ORCID 0000-0001-8298-7272
Raquel G HernandezDepartment of Pediatrics, Johns Hopkins School of Medicine.ORCID 0000-0002-0769-2770
Sara B JohnsonDepartment of Pediatrics, Johns Hopkins School of Medicine.ORCID 0000-0003-4532-1847
Brown University · USJohns Hopkins University · USDuke University · USIndiana University School of MedicineNC Department of Health and Human Services · US

Funding

Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI LAURA R STROUD · 2021 to 2026
$14.6M
Personalized Integrated Chronotherapy for Perinatal DepressionR01MH118269 · NIMH · RHODE ISLAND HOSPITAL · PI SHARKEY, KATHERINE M · 2020 to 2023
$5.1M
Social adversities, epigenetics, and the obesity epidemicR01MD011746 · NIMHD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE · 2017 to 2021
$4.4M
Prenatal stress and diet, and the fetal epigenomeR01MD017696 · NIMHD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Cathrine Hoyo · 2022 to 2026
$3.2M
Novel imprint control regions (ICRs) responsive to environmental exposuresR01ES032462 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE · 2021 to 2025
$3.0M
Longitudinal examination of DNA methylation in maltreated childrenR01HD095837 · NICHD · EMMA PENDLETON BRADLEY HOSPITAL · PI PARADE, STEPHANIE HART · 2018 to 2022
$2.8M
Research Training in Childhood Stress, Trauma, and ResilienceT32HD101392 · NICHD · MIRIAM HOSPITAL · PI PARADE, STEPHANIE HART, STROUD, LAURA R · 2020 to 2024
$1.7M
Development and implementation of a digital sleep intervention for preschoolers in foster careK01HL169495 · NHLBI · EMMA PENDLETON BRADLEY HOSPITAL · PI ROJO-WISSAR, DARLYNN MARIE · 2023 to 2024
$350k
NHLBI NIH HHS K01 HL169495NICHD NIH HHS R01 HD095837NICHD NIH HHS T32 HD101392NIEHS NIH HHS P30 E025128NIEHS NIH HHS P30 ES025128NIEHS NIH HHS R01 ES032462NIGMS NIH HHS P20 GM139767NIMHD NIH HHS R01 MD011746NIMHD NIH HHS R01 MD017696NIMH NIH HHS R01 MH118269
6 · The paper itself

Abstract

Maternal exposure to childhood adversity is associated with detrimental health outcomes throughout the lifespan and may have implications for offspring. Evidence links maternal adverse childhood experiences (ACEs) to detrimental birth outcomes, yet the impact on the infant's epigenome is unclear. Moreover, maternal sleep habits during pregnancy may influence this association. Here, we explore whether restless sleep during pregnancy moderates the association between exposure to maternal childhood adversity and infant epigenetic age acceleration in 332 mother-infant dyads (56% female; 39% Black; 25% Hispanic). During the 2

Indexed as

Adverse Childhood ExperiencesAgingEndothelial CellsEpigenesis, GeneticFemaleHumansInfantMaleMothersPregnancySleepAdverse Childhood ExperienceEpigenomicsPregnancySleep

Identifiers

PMID38601952
PMCPMC11003750
OpenAlexW4391321606

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.