Evidence map›Paper›PMID 38601138›Full record

ReviewRheumatology advances in practice2024

Current and future advances in practice: IgG4-related disease.

Zachary S Wallace, Guy Katz, Yasmin G Hernandez-Barco, Matthew C Baker

Open access · goldAbstract readReview
In one paragraph

Review in Rheumatology advances in practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
25.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Management of IgG4-Related Disease.Current rheumatology reports · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zachary S WallaceDivision of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
Guy KatzDivision of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0001-5370-4907
Yasmin G Hernandez-BarcoHarvard Medical School, Harvard University, Boston, MA, USA.
Matthew C BakerDivision of Immunology and Rheumatology, Stanford University, Palo Alto, CA, USA.ORCID https://orcid.org/0000-0002-0002-1907
Harvard University · USStanford University · US

Funding

Functions of the LKB1 tumor suppressor in control in metabolism and epigenticsR01CA215498 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL-BARDEESY, NABEEL · 2018 to 2022
$2.7M
NCI NIH HHS R01 CA215498
6 · The paper itself

Abstract

IgG4-related disease (IgG4-RD) is an increasingly recognized cause of fibroinflammatory lesions in patients of diverse racial and ethnic backgrounds and is associated with an increased risk of death. The aetiology of IgG4-RD is incompletely understood, but evidence to date suggests that B and T cells are important players in pathogenesis, both of which are key targets of ongoing drug development programmes. The diagnosis of IgG4-RD requires clinicopathological correlation because there is no highly specific or sensitive test. Glucocorticoids are highly effective, but their use is limited by toxicity, highlighting the need for studies investigating the efficacy of glucocorticoid-sparing agents. B cell-targeted therapies, particularly rituximab, have demonstrated benefit, but no randomized clinical trials have evaluated their efficacy. If untreated or under-treated, IgG4-RD can cause irreversible organ damage, hence close monitoring and consideration for long-term immunosuppression is warranted in certain cases.

Indexed as

epidemiologyglucocorticoidsIgG4-related diseaseoutcomesrituximabtreatment

Identifiers

PMID38601138
PMCPMC11003820
OpenAlexW4394698021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.