Evidence map›Paper›PMID 38601053›Full record

ArticleMedical hypothesis, discovery & innovation ophthalmology journal2023

Non-penetrating deep sclerectomy versus combined trabeculotomy-trabeculectomy in primary congenital glaucoma.

Ibrahim Hassan Elabd, Ahmed A Elsayed, Akram Fekry Elgazzar, Ezzeldin Ramadan Ezzeldin, Mohamed Hassanein, Haitham Beshr Soliman, Ashraf Mohammed GadElkareem, Basheer Eltantawy, Mohamed Yahia Omran, Mohamed Gaber Okasha and 6 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Medical hypothesis, discovery & innovation ophthalmology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Ibrahim Hassan ElabdDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Ahmed A ElsayedDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Akram Fekry ElgazzarDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Ezzeldin Ramadan EzzeldinDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Mohamed HassaneinDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Haitham Beshr SolimanDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Ashraf Mohammed GadElkareemDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Basheer EltantawyDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Mohamed Yahia OmranDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Mohamed Gaber OkashaDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Hatem MahmoudDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Ahmed Mohammed Madinah AlkadyDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Mahmoud H Abd RbuDepartment of Ophthalmology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt.
Hanan Saied HegazyDepartment of Ophthalmology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Mona N MansourDepartment of Ophthalmology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Ehab TharwatDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Al-Azhar University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The primary mode of therapy in children with primary congenital glaucoma (PCG) and mild or no corneal edema is goniotomy, which has a high success rate. However, in developing countries, the diagnosis of PCG is usually delayed, and corneal cloudiness interferes with goniotomy. Therefore, trabeculotomy may be the best choice in such eyes. We compared the short-term efficacy and safety of primary combined trabeculotomy-trabeculectomy (primary CTT) with that of non-penetrating deep sclerectomy (NPDS) in managing PCG. Methods: This prospective, randomized, comparative study included patients with PCG referred to Al-Azhar University Hospitals within a 1-year period. Eyes were randomly allocated to one of two groups: eyes in Results: Forty eyes of 26 patients were included, with 20 eyes allocated to each group. The mean (standard deviation) age of all patients was 12.9 (9.5) months, with comparable ages and sex ratios between groups (both Conclusions: CTT and NPDS both yielded reasonable IOP control and reversal of cupping in eyes with PCG. We observed equal effectiveness of the surgical procedures without major safety concerns. Further large-scale clinical trials with longer follow-up periods are needed to verify our preliminary findings.

Indexed as

corneaseye axial lengthintraocular pressuresnon-penetrating deep sclerectomyoptic discoptic nervesprimary congenital glaucoma type 3Btrabeculotomy

Identifiers

PMID38601053
PMCPMC11002464
OpenAlexW4394616433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.