ArticleLipids in health and disease2024
Association between obstructive sleep apnea and visceral adiposity index and lipid accumulation product: NHANES 2015-2018.
Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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51 citing papers in PubMed, 58 citations in OpenAlex.
- Exposure to environmental toxicants and obstructive sleep apnea: a cross-sectional study.Future science OA · 2026Article
- Parapharyngeal Fat Pads as an Obesity-Related Parameter for Apnea-Hypopnea Index Severity.Journal of sleep research · 2026Article
- Association between ln(FPG/HDL-C) × BMI and self-reported obstructive sleep apnea: A cross-sectional study using NHANES data.Medicine · 2026Article
- Integrating epidemiological and transcriptomic data reveals novel lipid metabolic drivers of obstructive sleep apnea.Nutrition & metabolism · 2026Article
- The inverse association between skeletal muscle mass to visceral fat ratio (SVR) and sleep disturbance: the mediating role of inflammation and aging acceleration.BMC psychiatry · 2026Article
- Association between lipid accumulation product and visceral adiposity index and rheumatoid arthritis: NHANES 1999-2018.Lipids in health and disease · 2026Article
- Associations between lipid accumulation indices and gallstone prevalence in Chinese elderly: a community-based study in Fuzhou.BMC gastroenterology · 2026Article
- Body fat percentage and hypertension risk: A population-based observational and Mendelian randomization study.Medicine · 2026Observational
- Risk stratification for gallstones based on 14 obesity and lipid-related Indices: a longitudinal cohort study of 44,030 Chinese adults.Lipids in health and disease · 2026Article
- Association between visceral adiposity index and risk of dental caries: findings from the national health and nutrition examination survey.Head & face medicine · 2026Article
- Weight-adjusted-waist index as a mediator in the association between atherogenic index of plasma and obstructive sleep apnoea: insights from NHANES 2015-2020.Journal of health, population, and nutrition · 2026Article
- Systemic inflammatory response index is associated with increased all-cause and cardiovascular mortality in obstructive sleep apnea: evidence from NHANES and validation with an external hospital-based dataset.Frontiers in medicine · 2026Article
- The Cardiometabolic Index (CMI) is associated with an increased risk of obstructive sleep apnea: a population-based study.European journal of medical research · 2025Article
- Improving cardiometabolic multimorbidity prediction with a composite obesity-TyG index: a study of middle-aged and older adults in CHARLS.Archives of public health = Archives belges de sante publique · 2025Article
- Physical activity reduces cancer mortality but not cardiovascular or all-cause mortality in obstructive sleep apnea: a National Health and Nutrition Examination Survey (NHANES)-based analysis.Journal of thoracic disease · 2025Article
- Association between age-adjusted visceral adiposity index and obstructive sleep apnea: a study based on NHANES 2015-2018.Journal of thoracic disease · 2025Article
- Assessing the association between multiple indicators of inflammation and sleep disorders in young and middle-aged women: insights from traditional and machine learning approaches.European journal of medical research · 2025Article
- Association between visceral lipid accumulation indicator and preserved ratio impaired spirometry in US adults: a population-based study from 2007 to 2012.Lipids in health and disease · 2025Article
- Association between relative fat mass and obstructive sleep apnea and the potential mediating effect of hypertension: based on NHANES 2005-2008 and 2015-2018.Nutrition journal · 2025Article
- Risk assessment and prevention of cardiovascular events in patients with obstructive sleep apnea syndrome: A narrative review.International journal of cardiology. Cardiovascular risk and prevention · 2025Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity refers to a significant contributor to the development of obstructive sleep apnea (OSA). Early prediction of OSA usually leads to better treatment outcomes, and this study aims to employ novel metabolic markers, visceral adiposity index (VAI), and lipid accumulation product (LAP) to evaluate the relationship to OSA.
methodsThe data used in the current cross-sectional investigation are from the National Health and Nutrition Examination Survey (NHANES), which was carried out between 2015 and 2018. To examine the correlation between LAP and VAI levels and OSA, multivariate logistic regression analysis was adopted. In addition, various analytical methods were applied, including subgroup analysis, smooth curve fitting, and threshold effect analysis.
resultsAmong totally 3932 participants, 1934 were included in the OSA group. The median (Q1-Q3) values of LAP and VAI for the participants were 40.25 (21.51-68.26) and 1.27 (0.75-2.21), respectively. Logistic regression studies indicated a positive correlation between LAP, VAI, and OSA risk after adjusting for potential confounding variables. Subgroup analysis revealed a stronger correlation between LAP, VAI levels, and OSA among individuals aged < 60 years. Through smooth curve fitting, specific saturation effects of LAP, VAI, and BMD were identified, with inflection points at 65.684 and 0.428, respectively.
conclusionThis study demonstrates that elevated levels of LAP and VAI increase the risk of OSA, suggesting their potential as predictive markers for OSA and advocating for dietary and exercise interventions to mitigate OSA risk in individuals with high LAP and VAI levels.
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