Evidence map›Paper›PMID 38600380›Full record

ArticleNature2024

Emergence of fractal geometries in the evolution of a metabolic enzyme.

Franziska L Sendker, Yat Kei Lo, Thomas Heimerl, Stefan Bohn, Louise J Persson, Christopher-Nils Mais, Wiktoria Sadowska, Nicole Paczia, Eva Nußbaum, María Del Carmen Sánchez Olmos and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  8. Symmetry facilitated the evolution of heterospecificity and high-order stoichiometry in vertebrate hemoglobin.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. ProSComputational and structural biotechnology journal · 2025
    Article
  10. Article
  11. Article
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  13. A local-global principle for nonequilibrium steady states.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Identifying nature's smallest fractals.Nature structural & molecular biology · 2024
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Franziska L SendkerEvolutionary Biochemistry Group, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0001-6311-0539
Yat Kei LoCenter for Synthetic Microbiology (SYNMIKRO), Philipps-University Marburg, Marburg, Germany.ORCID 0000-0002-9172-3196
Thomas HeimerlCenter for Synthetic Microbiology (SYNMIKRO), Philipps-University Marburg, Marburg, Germany.
Stefan BohnCryo-EM Platform and Institute of Structural Biology, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0001-9196-622X
Louise J PerssonDepartment of Chemistry - BMC, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-7300-4019
Christopher-Nils MaisDepartment of Chemistry, Philipps-University Marburg, Marburg, Germany.
Wiktoria SadowskaDepartment of Chemistry, University of Oxford, Oxford, UK.
Nicole PacziaDepartment of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0003-3859-8186
Eva NußbaumInterfaculty Institute of Microbiology and Infection Medicine, Organismic Interactions Department, Cluster of Excellence 'Controlling Microbes to Fight Infections', Tübingen University, Tübingen, Germany.
María Del Carmen Sánchez OlmosMaxGENESYS Biofoundry, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Karl ForchhammerInterfaculty Institute of Microbiology and Infection Medicine, Organismic Interactions Department, Cluster of Excellence 'Controlling Microbes to Fight Infections', Tübingen University, Tübingen, Germany.ORCID 0000-0003-3199-8101
Daniel SchindlerCenter for Synthetic Microbiology (SYNMIKRO), Philipps-University Marburg, Marburg, Germany.ORCID 0000-0001-7423-6540
Tobias J ErbCenter for Synthetic Microbiology (SYNMIKRO), Philipps-University Marburg, Marburg, Germany.ORCID 0000-0003-3685-0894
Justin L P BeneschDepartment of Chemistry, University of Oxford, Oxford, UK.ORCID 0000-0002-1507-3742
Erik G MarklundDepartment of Chemistry - BMC, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-9804-5009
Gert BangeCenter for Synthetic Microbiology (SYNMIKRO), Philipps-University Marburg, Marburg, Germany.ORCID 0000-0002-7826-0932
Jan M SchullerCenter for Synthetic Microbiology (SYNMIKRO), Philipps-University Marburg, Marburg, Germany. jan.schuller@synmikro.uni-marburg.de.ORCID 0000-0002-9121-1764
Georg K A HochbergEvolutionary Biochemistry Group, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany. georg.hochberg@mpi-marburg.mpg.de.ORCID 0000-0002-7155-0451
Philipps University of Marburg · DELoewe Center for Synthetic Microbiology · DEMax Planck Institute for Terrestrial Microbiology · DEUniversity of Oxford · GBUniversity of Tübingen · DEUppsala University · SEHelmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fractals are patterns that are self-similar across multiple length-scales

Indexed as

Citrate (si)-SynthaseEvolution, MolecularFractalsProtein MultimerizationSynechococcusCryoelectron MicroscopyModels, MolecularCitrate (si)-Synthase

Identifiers

PMID38600380
PMCPMC11041685
OpenAlexW4394694304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.