Evidence map›Paper›PMID 38600277›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2024

Relationship between changes in late-life blood pressure and the risk of frailty and mortality among older population in China: a cohort study based on CLHLS.

Yana Chen, Yanfang Wang, Yan Xu, Shunyao Shi, Zhong Tian, Kexin Jiang, Lina Jin, Yuchun Tao

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Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Blood pressure variability and arterial stiffness: the chicken or the egg?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  5. How does the precise prediction of preeclampsia onset aid the overall management of preeclampsia?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Yana ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Yanfang WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Yan XuDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Shunyao ShiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Zhong TianDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Kexin JiangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Lina JinDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Yuchun TaoDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China. tyc@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evidence regarding the effects of blood pressure changes on older individuals remains inconclusive, and the impact of frailty throughout the life course is not known. We investigated the associations of different change patterns of blood pressure during 3-year intervals with frailty and mortality. Participants included 7335 persons from 2008 to 2014 of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). Change in blood pressure was calculated as the difference between follow-up and baseline. Frailty was evaluated using a 40-item frailty index. Mortality status was ascertained up to December 31, 2014. The mean age of participants was 82.6 ± 10.7 years. The optimal blood pressure level (SBP, 130-150 mmHg; DBP, 70-90 mmHg) was associated with the lowest risk of frailty while decreasing follow-up SBP and DBP were significantly correlated with frailty. Lower baseline blood pressure levels (SBP < 130 mmHg; DBP < 70 mmHg) were associated with decreased mortality risk when participants increased their blood pressure to optimal levels during follow-up SBP and DBP (0.78, 0.63-0.98), compared to maintaining a steady low SBP (< 130 mmHg) and DBP (< 70 mmHg). For those with DBP around 70-90 mmHg, decreasing follow-up DBP (< 70 mmHg) was associated with higher mortality (1.23, 1.07-1.42) compared to maintaining stable follow-up DBP (70-90 mmHg). These results remain significant after adjusting for frailty. Optimal blood pressure levels were associated with the lowest risk of frailty. The association between lower blood pressure and increased mortality risk persisted even after accounting for frailty. We used a nationally representative longitudinal cohort study by using 2008-2014 of the Chinese Longitudinal Healthy Longevity in China. Change in blood pressure was calculated as the difference between follow-up and baseline. We investigated the associations of different change patterns of blood pressure during 3-year intervals with frailty and mortality.

Indexed as

Blood PressureFrailtyAgedAged, 80 and overChinaCohort StudiesFemaleFrail ElderlyHumansHypertensionLongevityLongitudinal StudiesMaleMortalityRisk FactorsChanges of blood pressureFrailtyFrailty indexMortality

Identifiers

PMID38600277

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.