Evidence map›Paper›PMID 38600134›Full record

ArticleScientific reports2024

Clinical, socio-demographic, and parental correlates of early autism traits in a community cohort of toddlers.

Oliver Gale-Grant, Andrew Chew, Shona Falconer, Lucas G S França, Sunniva Fenn-Moltu, Laila Hadaya, Nicholas Harper, Judit Ciarrusta, Tony Charman, Declan Murphy and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Oliver Gale-GrantDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK. oliver.gale-grant@kcl.ac.uk.
Andrew ChewCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
Shona FalconerCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
Lucas G S FrançaDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK.
Sunniva Fenn-MoltuDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK.
Laila HadayaCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
Nicholas HarperCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
Judit CiarrustaDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK.
Tony CharmanDepartment of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Declan MurphyDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK.
Tomoki ArichiCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
Grainne McAlonanDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK.
Chiara NosartiCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
A David EdwardsCentre for the Developing Brain, School of Imaging Sciences & Biomedical Engineering, King's College London, London, UK.
Dafnis BatalleDepartment of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16, De Crespigny Park, London, SE5 8AF, UK.
King's College London · GBImperial College London · GB

Funding

HORIZON EUROPE European Research Council FP7/20072013Medical Research Council MR/K006355/1Medical Research Council MR/N026063/1Medical Research Council MR/P008712/1Medical Research Council MR/V036874/1MRC MR/N013700/1MRC MR/P502108/1
6 · The paper itself

Abstract

Identifying factors linked to autism traits in the general population may improve our understanding of the mechanisms underlying divergent neurodevelopment. In this study we assess whether factors increasing the likelihood of childhood autism are related to early autistic trait emergence, or if other exposures are more important. We used data from 536 toddlers from London (UK), collected at birth (gestational age at birth, sex, maternal body mass index, age, parental education, parental language, parental history of neurodevelopmental conditions) and at 18 months (parents cohabiting, measures of socio-economic deprivation, measures of maternal parenting style, and a measure of maternal depression). Autism traits were assessed using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) at 18 months. A multivariable model explained 20% of Q-CHAT variance, with four individually significant variables (two measures of parenting style and two measures of socio-economic deprivation). In order to address variable collinearity we used principal component analysis, finding that a component which was positively correlated with Q-CHAT was also correlated to measures of parenting style and socio-economic deprivation. Our results show that parenting style and socio-economic deprivation correlate with the emergence of autism traits at age 18 months as measured with the Q-CHAT in a community sample.

Indexed as

Autism Spectrum DisorderAutistic DisorderChild, PreschoolEducational StatusFamily CharacteristicsHumansInfantParentingParents

Identifiers

PMID38600134
PMCPMC11006842
OpenAlexW4394691633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.