Evidence map›Paper›PMID 38599867›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Successful Pregnancy and Delivery after Frozen-thawed Embryo Transfer Following the Third Discontinuation of Tyrosine Kinase Inhibitor in a Woman with Chronic Myeloid Leukemia.

Kosuke Takayama, Shin Fujisawa, Takayuki Sakuma, Kodai Hasegawa, Kengo Katsuki, Masahiro Akimoto, Ayako Matsumura, Yuki Nakajima, Takuya Miyazaki, Mariko Murase and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kosuke TakayamaDepartment of Hematology, Yokohama City University Medical Center, Japan.
Shin FujisawaDepartment of Hematology, Yokohama City University Medical Center, Japan.
Takayuki SakumaDepartment of Hematology, Yokohama City University Medical Center, Japan.
Kodai HasegawaDepartment of Hematology, Yokohama City University Medical Center, Japan.
Kengo KatsukiDepartment of Hematology, Yokohama City University Medical Center, Japan.
Masahiro AkimotoDepartment of Hematology, Yokohama City University Medical Center, Japan.
Ayako MatsumuraDepartment of Hematology, Yokohama City University Medical Center, Japan.
Yuki NakajimaDepartment of Hematology, Yokohama City University Medical Center, Japan.
Takuya MiyazakiDepartment of Hematology, Yokohama City University Medical Center, Japan.
Mariko MuraseReproductive Medicine Center, Yokohama City University Medical Center, Japan.
Hideaki NakajimaDepartment of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assisted reproductive technology is a viable option for pregnant women with chronic myeloid leukemia. We herein report the case of a patient who underwent successful fertility treatment with frozen embryo preservation at 36 years of age, followed by embryo transfer at 39 years of age, thus resulting in pregnancy and delivery after a third discontinuation of tyrosine kinase inhibitors (TKIs). Despite the difficulty of long-term TKI withdrawal, the patient's strong desire for a baby led to a successful pregnancy and delivery with no apparent deformities or abnormalities. Thus, our case highlights the importance of collaboration between reproductive medicine physicians and hematologists.

Indexed as

CryopreservationEmbryo TransferLeukemia, Myelogenous, Chronic, BCR-ABL PositiveProtein Kinase InhibitorsAdultFemaleHumansPregnancyPregnancy Complications, NeoplasticPregnancy OutcomeTyrosine Kinase InhibitorsProtein Kinase InhibitorsTyrosine Kinase Inhibitorsassisted reproductive technologychronic myeloid leukemiapregnancytyrosine kinase inhibitor

Identifiers

PMID38599867
PMCPMC11671195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.