Evidence map›Paper›PMID 38599864›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Drug-induced Steatohepatitis Caused by Long-term Use of Topical Steroids for Atopic Dermatitis.

Yuki Tamura, Atsushi Naganuma, Yuhei Suzuki, Sanae Uehara, Takashi Hoshino, Takeshi Hatanaka, Nobuyuki Shibusawa, Akihito Uehara, Akira Ogawa, Satoru Kakizaki and 1 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuki TamuraDepartment of Gastroenterology, NHO Takasaki General Medical Center, Japan.
Atsushi NaganumaDepartment of Gastroenterology, NHO Takasaki General Medical Center, Japan.
Yuhei SuzukiDepartment of Gastroenterology, NHO Takasaki General Medical Center, Japan.
Sanae UeharaDepartment of Gastroenterology, NHO Takasaki General Medical Center, Japan.
Takashi HoshinoDepartment of Gastroenterology, NHO Takasaki General Medical Center, Japan.
Takeshi HatanakaDepartment of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Japan.
Nobuyuki ShibusawaDepartment of Endocrinology and Metabolism, NHO Takasaki General Medical Center, Japan.
Akihito UeharaDepartment of Dermatology, NHO Takasaki General Medical Center, Japan.
Akira OgawaDepartment of Pathology, NHO Takasaki General Medical Center, Japan.
Satoru KakizakiDepartment of Gastroenterology, NHO Takasaki General Medical Center, Japan.
Toshio UraokaDepartment of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis is common in children and often treated with topical corticosteroids (TCs). A boy in his late teens who had been using TCs for atopic dermatitis was diagnosed with liver damage during a health checkup. A medical examination revealed severe steatotic liver disease and elevated liver enzyme levels despite the absence of typical symptoms such as central obesity. After discontinuation of TCs, an improvement in liver enzyme levels was observed, leading to the diagnosis of drug-induced steatohepatitis. This case underscores the potential liver risks associated with prolonged TC use in children, highlighting the need for parental education.

Indexed as

Dermatitis, AtopicAdministration, TopicalAdolescentAdrenal Cortex HormonesChemical and Drug Induced Liver InjuryFatty LiverHumansMaleTime FactorsAdrenal Cortex Hormonesatopic dermatitisdrug-induced steatohepatitissteatohepatitistopical corticosteroids

Identifiers

PMID38599864
PMCPMC11671201

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.