Evidence map›Paper›PMID 38599533›Full record

ArticleJournal of pain and symptom management2024

Clinician Ordering and Management Patterns of Urine Toxicology Results at a Cancer Center.

Miryam Yusufov, Stacy E F Melanson, Phillip Kang, Benjamin Kematick, Gordon D Schiff, Isaac S Chua

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miryam YusufovDepartment of Psychosocial Oncology and Palliative Care (M.Y., B.K., I.S.C.), Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Harvard Medical School (M.Y., S.E.F.M., G.D.S., I.S.C.), Boston, Massachusetts, USA.
Stacy E F MelansonDepartment of Pathology (S.E.F.M., P.K.), Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School (M.Y., S.E.F.M., G.D.S., I.S.C.), Boston, Massachusetts, USA.
Phillip KangDepartment of Pathology (S.E.F.M., P.K.), Brigham and Women's Hospital, Boston, Massachusetts, USA.
Benjamin KematickDepartment of Psychosocial Oncology and Palliative Care (M.Y., B.K., I.S.C.), Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Gordon D SchiffCenter for Patient Safety Research and Practice (G.D.S.), Brigham and Women's Hospital, Boston, Massachusetts, USA; Department of Medicine (G.D.S., I.S.C.), Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School (M.Y., S.E.F.M., G.D.S., I.S.C.), Boston, Massachusetts, USA; Harvard Medical School Center for Primary Care (G.D.S.), Boston, Massachusetts, USA.
Isaac S ChuaDepartment of Psychosocial Oncology and Palliative Care (M.Y., B.K., I.S.C.), Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Department of Medicine (G.D.S., I.S.C.), Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School (M.Y., S.E.F.M., G.D.S., I.S.C.), Boston, Massachusetts, USA. Electronic address: ichua@bwh.harvard.edu.

Funding

A Novel Intervention for Avoidance-Related Opioid Misuse in Patients with CancerK08CA259538 · NCI · DANA-FARBER CANCER INST · PI Miryam Yusufov · 2022 to 2026
$787k
NCI NIH HHS K08 CA259538NCI NIH HHS L30 CA242689
6 · The paper itself

Abstract

contextOpioid therapy is a cornerstone for treatment of cancer-related pain, but standardized management practices for patients with cancer and aberrant urine drug test (UDT) results are lacking.

objectivesTo identify the prevalence of UDT ordering (both screening and definitive testing) in the oncology setting and to examine clinician management practices for patients with cancer on opioid therapy with aberrant definitive UDT results.

methodsWe conducted a retrospective chart review of patients with cancer on opioid therapy at an academic cancer center in the United States. Outcomes included UDT ordering patterns and clinician management practices in response to aberrant definitive UDT results.

resultsOur study revealed an overall UDT ordering rate of 3.7% among 10,371 patients with cancer on opioid therapy. Among 143 patients for whom definitive UDTs were ordered, oncologists only ordered 14 (9.8%) UDTs, while palliative care ordered the majority (n = 129; 90.2%). Fifty-five (38.5%) patients had aberrant results, and the most common aberrancy was presence of illicit drugs 22 [15.4%]. Clinicians rarely made medication changes (20 [36.4%]) when UDT results were aberrant, and in the setting of possible fentanyl use (n = 8), only 3 (37.5%) patients were started/switched to methadone, and none were started/switched to buprenorphine.

conclusionOverall UDT ordering was infrequent for patients with cancer on opioid therapy, especially by oncologists, and clinicians rarely made prescribing changes when definitive UDT results were aberrant. More definitive guidance related to UDT ordering and opioid management are needed for patients with cancer and aberrant UDT results.

Indexed as

Analgesics, OpioidCancer PainPractice Patterns, Physicians'AdultAgedCancer Care FacilitiesFemaleHumansMaleMiddle AgedNeoplasmsPalliative CareRetrospective StudiesSubstance Abuse DetectionAnalgesics, OpioidOncologyOpioidUrine drug testing

Identifiers

PMID38599533
PMCPMC13166046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.