Evidence map›Paper›PMID 38598472›Full record

ArticlePloS one2024

The impact of size on middle-ear sound transmission in elephants, the largest terrestrial mammal.

Caitlin E O'Connell-Rodwell, Jodie L Berezin, Anbuselvan Dharmarajan, Michael E Ravicz, Yihan Hu, Xiying Guan, Kevin N O'Connor, Sunil Puria

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Caitlin E O'Connell-RodwellEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0002-2532-9326
Jodie L BerezinEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.
Anbuselvan DharmarajanEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.
Michael E RaviczEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0001-9978-3444
Yihan HuEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.
Xiying GuanSchool of Medicine, Wayne State University, Detroit, Michigan, United States of America.
Kevin N O'ConnorEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.
Sunil PuriaEaton-Peabody Laboratories, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States of America.
Massachusetts Eye and Ear Infirmary · USWayne State University · US

Funding

Ossicular Mechanics of a Low Frequency Ear and Implications for Bone-Conducted Hearing.K01DC017812 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI O'CONNELL-RODWELL, CAITLIN · 2019 to 2023
$708k
NIDCD NIH HHS K01 DC017812
6 · The paper itself

Abstract

Elephants have a unique auditory system that is larger than any other terrestrial mammal. To quantify the impact of larger middle ear (ME) structures, we measured 3D ossicular motion and ME sound transmission in cadaveric temporal bones from both African and Asian elephants in response to air-conducted (AC) tonal pressure stimuli presented in the ear canal (PEC). Results were compared to similar measurements in humans. Velocities of the umbo (VU) and stapes (VST) were measured using a 3D laser Doppler vibrometer in the 7-13,000 Hz frequency range, stapes velocity serving as a measure of energy entering the cochlea-a proxy for hearing sensitivity. Below the elephant ME resonance frequency of about 300 Hz, the magnitude of VU/PEC was an order of magnitude greater than in human, and the magnitude of VST/PEC was 5x greater. Phase of VST/PEC above ME resonance indicated that the group delay in elephant was approximately double that of human, which may be related to the unexpectedly high magnitudes at high frequencies. A boost in sound transmission across the incus long process and stapes near 9 kHz was also observed. We discuss factors that contribute to differences in sound transmission between these two large mammals.

Indexed as

ElephantsAnimalsEar, MiddleHearingHumansSoundStapesVibration

Identifiers

PMID38598472
PMCPMC11006165
OpenAlexW4394694313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.