ArticleWorld journal of urology2024
A new protocol for renal collecting system sterilization with antibiotic irrigation during lithotripsy in retrograde intrarenal surgery: a prospective, comparative study.
Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Intrarenal antimicrobial irrigation as an adjunct to systemic prophylaxis in upper tract endourology: a PRISMA-ScR scoping review of a limited and heterogeneous evidence base.World journal of urology · 2026Article
- Urinary Tract Infectious Complications After Retrograde Intrarenal Surgery: The RIRS-STAMP Risk Score from a Two-Center Cohort.Pathogens (Basel, Switzerland) · 2026Article
- A new protocol to reduce postoperative infections for retrograde intrarenal surgery: irrigating antibiotic in renal collecting system.World journal of urology · 2024Article
- Letter to the editor for the article "A new protocol for renal collecting system sterilization with antibiotic irrigation during lithotripsy in retrograde intrarenal surgery: a prospective, comparative study".World journal of urology · 2024Article
- Administering antibiotic-loaded irrigation fluid as an alternative for prophylactic intravenous antibiotics in transurethral ureterolithotripsy (TUL): a randomized controlled trial.American journal of clinical and experimental urology · 2024Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo present a new protocol using antibiotic irrigation during lithotripsy in retrograde intrarenal surgery (RIRS) to provide sterility of the renal collecting system.
methodsThis prospective study included 102 patients who underwent RIRS between January 2022 and August 2023. The patients were examined in two groups as those who received antibiotic irrigation (n:51) and standard irrigation (n:51). In the antibiotic irrigation group, 80 mg of gentamicin was dissolved in normal saline in a 3 L irrigation pouch to obtain a 26.7 mg/L concentration. In the standard irrigation group, normal saline was used. Preoperative information, including age, sex, body mass index (BMI), ASA score, stone side, volume, and density, and the Seoul National University Renal Stone Complexity (S-ReSC) score. The groups were compared with respect to postoperative fever (> 38 °C), urinary tract infection (UTI), systemic inflammatory response syndrome (SIRS), infectious complications such as sepsis, and stone-free rate.
resultsNo statistically significant difference was determined between the groups with respect to age, sex, BMI, ASA score, stone side, volume and density, and S-ReSC score (p > 0.05 for all). Statistically significant differences were determined between the groups with respect to postoperative fever (p = 0.05), SIRS (p = 0.05), and hospital length of stay (p = 0.05). Sepsis was observed in one patient in the standard irrigation group and in none of the antibiotic irrigation group.
conclusionThe reliability, efficacy, and utility of antibiotic irrigation during lithotripsy in RIRS were presented in this study as a new protocol for sterilization of the renal collecting system which will be able to reduce infectious complications.
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