ArticleIntensive care medicine2024
Association between arterial oxygen and mortality across critically ill patients with hematologic malignancies: results from an international collaborative network.
Article in Intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
- Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation.Intensive care medicine · 2024Trial
- Article
- Article
- Extreme temperature events exposure and risks of stillbirths: nationwide large birth cohort study in China.Environment international · 2025Article
- Temporal dimensions of oxygen saturation exposure and clinical outcomes in critically ill patients: a retrospective multi-database cohort study.Critical care (London, England) · 2025Article
- Contemporary review of critical illness following allogeneic hematopoietic stem cell transplant in adults.Intensive care medicine · 2025Review
- [The value of sequential organ failure assessment and its dynamic changes in predicting mortality in hematology intensive care unit].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2025Article
- Oxygen targets in patients with septic shock: a retrospective cohort study on the association between hyperoxia and mortality.Frontiers in medicine · 2025Article
- Oxygen thresholds in critically ill patients: need for personalized targets. Author's reply.Intensive care medicine · 2024Article
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients with hematological malignancies are at high risk for life-threatening complications. To date, little attention has been paid to the impact of hyperoxemia and excess oxygen use on mortality. The aim of this study was to investigate the association between partial pressure of arterial oxygen (PaO
methodsData from three international cohorts (Europe, Canada, Oceania) of patients who received respiratory support (noninvasive ventilation, high-flow nasal cannula, invasive mechanical ventilation) were obtained. We used mixed-effect Cox models to investigate the association between day one PaO
results11,249 patients were included. On day one, 5716 patients (50.8%) had normoxemia (60 ≤ PaO
conclusionIn critically-ill patients with hematological malignancies, exposure to hyperoxemia and excess oxygen use were associated with increased mortality, with variable magnitude across subgroups. This might be a modifiable factor to improve mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.