Evidence map›Paper›PMID 38598093›Full record

ArticleMedical physics2024

Technical note: Visual, rapid, scintillation point dosimetry for in vivo MV photon beam radiotherapy treatments.

Savannah M Decker, Petr Bruza, Rongxiao Zhang, Benjamin B Williams, Lesley A Jarvis, Brian W Pogue, David J Gladstone

Open access · bronzeAbstract read
In one paragraph

Article in Medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Savannah M DeckerThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Petr BruzaThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Rongxiao ZhangGeisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Benjamin B WilliamsDartmouth Cancer Center, Dartmouth Health, Lebanon, New Hampshire, USA.
Lesley A JarvisGeisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
David J GladstoneThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA.
Dartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
OPTICAL CHERENKOV IMAGING DOSIMETRY IN HUMAN RADIOTHERAPYR01EB023909 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI GLADSTONE, DAVID J., JARVIS, LESLEY A · 2017 to 2024
$4.4M
Everyday Use of Optical Cherenkov Imaging Identifies Adverse Events and Opportunities for Improved Radiation TreatmentR44CA265654 · NCI · DOSEOPTICS, LLC · PI WARE, WILLIAM · 2021 to 2022
$2.0M
Improving the Inclusivity of Cherenkov Imaging in Radiotherapy for Diverse Patient GroupsF31EB034181 · NIBIB · DARTMOUTH COLLEGE · PI DECKER, SAVANNAH MARIE · 2022 to 2023
$86k
NCI NIH HHS P30 CA023108NCI NIH HHS R44 CA265654NIBIB NIH HHS F31 EB034181NIBIB NIH HHS R01 EB023909NIH HHS F31 EB034181NIH HHS P30 CA023108NIH HHS R01 EB023909NIH HHS R44 CA265654
6 · The paper itself

Abstract

backgroundWhile careful planning and pre-treatment checks are performed to ensure patient safety during external beam radiation therapy (EBRT), inevitable daily variations mean that in vivo dosimetry (IVD) is the only way to attain the true delivered dose. Several countries outside the US require daily IVD for quality assurance. However, elsewhere, the manual labor and time considerations of traditional in vivo dosimeters may be preventing frequent use of IVD in the clinic. PURPOSE: This study expands upon previous research using plastic scintillator discs for optical dosimetry for electron therapy treatments. We present the characterization of scintillator discs for in vivo x-ray dosimetry and describe additional considerations due to geometric complexities.

methodsPlastic scintillator discs were coated with reflective white paint on all sides but the front surface. An anti-reflective, matte coating was applied to the transparent face to minimize specular reflection. A time-gated iCMOS camera imaged the discs under various irradiation conditions. In post-processing, background-subtracted images of the scintillators were fit with Gaussian-convolved ellipses to extract several parameters, including integral output, and observation angle.

resultsDose linearity and x-ray energy independence were observed, consistent with ideal characteristics for a dosimeter. Dose measurements exhibited less than 5% variation for incident beam angles between 0° and 75° at the anterior surface and 0-60

conclusionsPlastic scintillator discs have characteristics that are well-suited for in vivo optical dosimetry for x-ray radiotherapy treatments. Unlike typical point dosimeters, there is no inherent readout time delay, and an optical recording of the measurement is saved after treatment for future reference. While several factors influence the integral output for the same dose, they have been quantified here and may be corrected in post-processing.

Indexed as

PhotonsScintillation CountingHumansRadiometryRadiotherapyRadiotherapy DosageTime Factorsin vivo dosimetryphoton therapyscintillation imaging

Identifiers

PMID38598093
PMCPMC11321933
OpenAlexW4394676529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.