Evidence map›Paper›PMID 38598035›Full record

ReviewCurrent oncology reports2024

Advances in Radionuclide Therapies for Patients with Neuro-endocrine Tumors.

Denise S Hoogenkamp, Linda J de Wit-van der Veen, Daphne M V Huizing, Margot E T Tesselaar, Rachel S van Leeuwaarde, Marcel P M Stokkel, Marnix G E H Lam, Arthur J A T Braat

Open access · hybridAbstract readReview
In one paragraph

Review in Current oncology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Denise S HoogenkampDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Linda J de Wit-van der VeenDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Daphne M V HuizingDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Margot E T TesselaarENETS Center of Excellence NKI-AVL, The Netherlands Cancer Institute/UMC Utrecht, Amsterdam, The Netherlands.
Rachel S van LeeuwaardeENETS Center of Excellence NKI-AVL, The Netherlands Cancer Institute/UMC Utrecht, Amsterdam, The Netherlands.
Marcel P M StokkelDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Marnix G E H LamENETS Center of Excellence NKI-AVL, The Netherlands Cancer Institute/UMC Utrecht, Amsterdam, The Netherlands.
Arthur J A T BraatDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands. a.j.a.t.braat@umcutrecht.nl.
Cancer Genomics Centre · NLThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo provide insights into the role of peptide receptor radionuclide therapy (PRRT) in patients with advanced neuroendocrine tumors (NET) and an overview of possible strategies to combine PRRT with locoregional and systemic anticancer treatments. RECENT

findingsResearch on combining PRRT with other treatments encompasses a wide variety or treatments, both local (transarterial radioembolization) and systemic therapies, chemotherapy (i.e., capecitabine and temozolomide), targeted therapies (i.e., olaparib, everolimus, and sunitinib), and immunotherapies (e.g., nivolumab and pembrolizumab). Furthermore, PRRT shows promising first results as a treatment prior to surgery. There is great demand to enhance the efficacy of PRRT through combination with other anticancer treatments. While research in this area is currently limited, the field is rapidly evolving with numerous ongoing clinical trials aiming to address this need and explore novel therapeutic combinations.

Indexed as

Neuroendocrine TumorsCombined Modality TherapyHumansRadioisotopesRadiopharmaceuticalsReceptors, PeptideRadioisotopesRadiopharmaceuticalsReceptors, PeptideCombination therapyNeuroendocrine tumorPeptide receptor radionuclide therapyRadioembolization

Identifiers

PMID38598035
PMCPMC11062977
OpenAlexW4394686126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.