Evidence map›Paper›PMID 38597672›Full record

ArticleAntimicrobial agents and chemotherapy2024

Cefadroxil and cephalexin pharmacokinetics and pharmacodynamics in children with musculoskeletal infections.

Andrew S Haynes, Zixuan Wei, Peter Anderson, Marc H Scheetz, Sarah K Parker, Douglas N Fish

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Development ofDiscover nano · 2026
    Article
  2. Review
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  6. Review
  7. Beta-lactam combination treatment overcomes rifampicin resistance in Mycobacterium tuberculosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew S HaynesChildren's Hospital Colorado, Department of Pediatrics, Section of Pediatric Infectious Diseases, Aurora, Colorado, USA.ORCID 0000-0001-5486-0522
Zixuan WeiUniversity of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA.
Peter AndersonUniversity of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA.
Marc H ScheetzMidwestern University, Pharmacometrics Center of Excellence, Colleges of Pharmacy and Pharmacology, Downers Grove, Illinois, USA.ORCID 0000-0002-1091-6130
Sarah K ParkerChildren's Hospital Colorado, Department of Pediatrics, Section of Pediatric Infectious Diseases, Aurora, Colorado, USA.
Douglas N FishUniversity of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA.
Children's Hospital Colorado · USMidwestern University · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Novel approaches for quantitative assessment of adherenceR01AI122298 · NIAID · UNIVERSITY OF COLORADO DENVER · PI ANDERSON, PETER L. · 2016 to 2020
$3.4M
Clinical Pharmacology K12 Training ProgramK12HD113190 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI TRACY A GLAUSER, Sonya C Tang Girdwood · 2023 to 2026
$1.2M
NCATS NIH HHS UL1 TR002535NIAID NIH HHS R01 AI122298NICHD NIH HHS K12 HD113190
6 · The paper itself

Abstract

Cephalexin, a first-generation cephalosporin, is the first-line oral therapy for children with musculoskeletal infections due to methicillin-susceptible

Indexed as

Anti-Bacterial AgentsCefadroxilCephalexinCross-Over StudiesMicrobial Sensitivity TestsAdolescentChildChild, PreschoolFemaleHumansInfantMaleProspective StudiesStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsCefadroxilCephalexincefadroxilcephalexinosteomyelitispediatric drug therapypediatric infectious diseasepharmacodynamicspharmacokinetics

Identifiers

PMID38597672
PMCPMC11064491
OpenAlexW4394692546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.