Evidence map›Paper›PMID 38597552›Full record

ArticleArquivos brasileiros de cardiologia2024

Testosterone Deficiency in Hypertensive Men: Prevalence and Associated Factors.

Leandra Analia Freitas Negretto, Nelson Rassi, Leonardo Ribeiro Soares, Amanda Bueno Carvalho Saraiva, Maria Emília Figueiredo Teixeira, Luciana da Ressurreição Santos, Ana Luiza Lima Souza, Paulo Cesar B Veiga Jardim, Weimar Kunz Sebba Barroso de Souza, Thiago de Souza Veiga Jardim

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Leandra Analia Freitas NegrettoUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.ORCID 0000-0003-2678-4715
Nelson RassiHospital Geral de Goiânia - Dr. Alberto Rassi, Goiânia, GO - Brasil.ORCID 0009-0006-2145-3377
Leonardo Ribeiro SoaresUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.
Amanda Bueno Carvalho SaraivaUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.
Maria Emília Figueiredo TeixeiraUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.ORCID 0000-0002-4785-9651
Luciana da Ressurreição SantosUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.
Ana Luiza Lima SouzaUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.
Paulo Cesar B Veiga JardimUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.ORCID 0000-0002-5333-013X
Weimar Kunz Sebba Barroso de SouzaUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.
Thiago de Souza Veiga JardimUniversidade Federal de Goiás - Liga de Hipertensão Arterial, Goiânia, GO - Brasil.
Universidade Federal de Goiás · BRArtistic Realization Technologies · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTestosterone deficiency (TD) is a prevalent condition in our midst and still very neglected. Arterial hypertension (AH) is one of the possible associated factors.

objectivesTo determine the prevalence of TD in a hypertensive male population and the factors associated with its occurrence, such as age, time since hypertension diagnosis, number of antihypertensive classes, body mass index (BMI), diabetes, dyslipidemia, chronic kidney disease (CKD), positive symptoms of TD (positive ADAM questionnaire) and use of spironolactone.

methodsCross-sectional study with administration of the ADAM questionnaire, assessment of biochemical, clinical, and anthropometric data. Patients were stratified into DT and normal testosterone groups. Categorical variables were compared using the chi-squared test and continuous variables using the Mann-Witney test; variables with significance (p<0,05) were analyzed by multivariable linear regression.

resultsThe prevalence of TD was 26.36%. There was an association between TD and body mass index (BMI) (p=0.0007) but there was no association with age (p=0.0520), time of hypertension diagnosis (p=0.1418), number of classes of antihypertensive drugs (p=0.732), diabetes (p=0.1112); dyslipidemia (p=0.3888); CKD (p=0.3321); use of spironolactone (p=0.3546) or positive ADAM questionnaire (p=0.2483).

conclusionsTD was highly prevalent and positively associated with BMI. Total testosterone (TT) declined by 8.44ng/dL with a one unit increase in BMI and dropped by 3.79ng/dL with a one-year increase in age.

Indexed as

Diabetes MellitusDyslipidemiasHypertensionRenal Insufficiency, ChronicCross-Sectional StudiesHumansMalePrevalenceSpironolactoneTestosteroneSpironolactoneTestosterone

Identifiers

PMID38597552
PMCPMC12094286
OpenAlexW4394768440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.