Evidence map›Paper›PMID 38596992›Full record

ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2022

Expression and significance of mucin-4 and matrix metalloproteinase-7 in peri-implant disease.

Dandan Jiang, Zheng Zhou, Yufeng Shen, Xiaoxue Tang, Xiaorui Gou, Meiyu Huang, Yizhou Tong, Miaomiao Chen, Chong-Qing Yu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dandan JiangDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Zheng ZhouDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Yufeng ShenDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Xiaoxue TangDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Xiaorui GouDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Meiyu HuangDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Yizhou TongDept. of Stomatology, Shihezi University, Shihezi 832000, China.
Miaomiao ChenDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
Chong-Qing YuDept. of Stomatology, the First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, China.
First Affiliated Hospital of Shihezi University Medical College · CNShihezi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to detect the levels of mucin (MUC)-4, metalloproteinase (MMP)-7, and MMP-8 in peri-implant crevicular fluid (PICF) and investigate whether the novel combinations of MMP-7 and MUC-4 are effective markers of peri-implant diseases, particularly when used in the PICF of healthy individuals, to provide a theoretical basis for finding a novel reference index that can aid the diagnosis, evaluation, and treatment of peri-implant diseases.

methodsA total of 63 subjects with 2-5 years of upper prosthesis loading were selected according to inclusion and exclusion criteria, composed of 24 controls and 39 patients with peri-implantitis (PI) group. MUC-4, MMP-7, and MMP-8 levels were detected through enzyme linked immunosorbent assay (ELISA).

resultsNo significant differences in age, sex, and other parameters were found between the PI and control groups. The PI group had higher MMP-7 and MMP-8 expression levels (

conclusionsDifferences in MMP-7 and MUC-4 levels were found between the inflammation and control groups and may be diagnostic indicators for predicting PI; combinations of MMP-7 and MUC-4 had a good diagnostic value for inflammation.

Indexed as

matrix metalloproteinase-7mucin-4peri-implant disease

Identifiers

PMID38596992
PMCPMC8905267
OpenAlexW4394766761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.