Evidence map›Paper›PMID 38596900›Full record

ArticleThe veterinary quarterly2024

Fatal tick-borne encephalitis virus infection in Dalmatian puppy-dogs after putative vector independent transmission.

Kara L D Dawson, Giuliana Rosato, Simone Egloff, Carole Burgener, Anna Oevermann, Paula Grest, Monika Hilbe, Torsten Seuberlich

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The veterinary quarterly, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kara L D DawsonDivision of Neurological Sciences, Vetsuisse Faculty, University of Bern, Bern, Switzerland.ORCID 0000-0002-3531-7476
Giuliana RosatoInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.ORCID 0009-0005-2302-558X
Simone EgloffClinic of Reproductive Medicine, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Carole BurgenerInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Anna OevermannDivision of Neurological Sciences, Vetsuisse Faculty, University of Bern, Bern, Switzerland.ORCID 0000-0002-3569-8547
Paula GrestInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Monika HilbeInstitute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4133-2402
Torsten SeuberlichDivision of Neurological Sciences, Vetsuisse Faculty, University of Bern, Bern, Switzerland.ORCID 0000-0002-6800-5129
University of Zurich · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a retrospective metatranscriptomics study, we identified tick-borne encephalitis virus (TBEV) to be the causative agent for a fatal non-suppurative meningoencephalitis in a three-week-old Dalmatian puppy in Switzerland. Further investigations showed that the two other littermates with similar signs and pathological lesions were also positive for TBEV. By using an unbiased approach of combining high-throughput sequencing (HTS) and bioinformatics we were able to solve the etiology and discover an unusual case of TBEV in three young puppies. Based on our findings, we suggest that a vector-independent transmission of TBEV occurred and that most likely an intrauterine infection led to the severe and fulminant disease of the entire litter. We were able to demonstrate the presence of TBEV RNA by

Indexed as

Dog DiseasesEncephalitis, Tick-BorneEncephalitis Viruses, Tick-BorneAnimalsDogsRetrospective StudiesRNARNAhigh-throughput sequencingmetatranscriptomicspuppiesTick-borne encephalitis virus

Identifiers

PMID38596900
PMCPMC11008312
OpenAlexW4394690551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.