Evidence map›Paper›PMID 38596746›Full record

ArticleJournal of experimental pharmacology2024

Nephroprotective Effect of the Leaf Extract of

Metages Ayele Akinaw, Suresh Kumar P Nair, Rashed Edris Usure, Bati Leta, Abdo Kedir, Selam Ayele Mamo, Nuredin Chura Waritu, Mohammed Jemal, Berhane Kebede Mulat

Open access · goldAbstract read
In one paragraph

Article in Journal of experimental pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Metages Ayele AkinawDepartment of Biomedical Sciences, School of Medicine, Jimma University, Jimma, Ethiopia.
Suresh Kumar P NairDepartment of Biomedical Sciences, School of Medicine, Jimma University, Jimma, Ethiopia.
Rashed Edris UsureDepartment of Pharmaceutical Chemistry, School of Pharmacy, Hawassa University, Hawassa, Ethiopia.
Bati LetaDepartment of Biomedical Sciences, School of Medicine, Jimma University, Jimma, Ethiopia.ORCID 0000-0002-4499-7098
Abdo KedirDepartment of Pathology, School of Medicine, Jimma University, Jimma, Ethiopia.ORCID 0000-0002-8466-372X
Selam Ayele MamoDepartment of Adult Health Nursing, School of Nursing, Jimma University, Jimma, Ethiopia.
Nuredin Chura WarituDepartment of Biomedical Sciences, School of Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.ORCID 0009-0000-1468-4640
Mohammed JemalDepartment of Biomedical Sciences, School of Medicine, Debre Merkos University, Debre Merkos, Ethiopia.ORCID 0009-0000-6700-9972
Berhane Kebede MulatDepartment of Biomedical Sciences, School of Medicine, Jimma University, Jimma, Ethiopia.
Jimma University · ETDebre Tabor University · ETHawassa University · ETWolaita Sodo University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Drug-induced kidney injury was among the most common renal damages, from which gentamicin occupies around 25% of this injury. Gentamicin-induced renal damage is caused by increased free radicals with subsequent amplified inflammation. Methods: An experimental study design was used on 30 experimental mice randomly allocated in six groups: Group I, II, II, IV, and VI, among which mice were given only distilled water, only gentamicin, 600 mg/kg Results: Group II mice had significantly higher levels of serum creatinine and blood urea levels compared to group I and III. The body weight of the mice in group V and group VI showed a significant increase compared with Group II. Serum creatinine and blood urea levels were reduced significantly in the Conclusion: Methanol extract of

Indexed as

Ajuga remota Benthgentamicinmethanolnephrotoxicity

Identifiers

PMID38596746
PMCPMC11001546
OpenAlexW4393182632

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.