Evidence map›Paper›PMID 38596720›Full record

ArticleJournal of applied crystallography2024

The

Gihan Ketawala, Caitlin M Reiter, Petra Fromme, Sabine Botha

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied crystallography, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gihan KetawalaBiodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85287-5001, USA.ORCID https://orcid.org/0000-0002-9436-3536
Caitlin M ReiterNSF BioXFEL Science and Technology Center Summer Internship Program, NY 14203, USA.
Petra FrommeBiodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85287-5001, USA.
Sabine BothaBiodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85287-5001, USA.
Arizona State University · USBioXFEL Science and Technology Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data collection at X-ray free electron lasers has particular experimental challenges, such as continuous sample delivery or the use of novel ultrafast high-dynamic-range gain-switching X-ray detectors. This can result in a multitude of data artefacts, which can be detrimental to accurately determining structure-factor amplitudes for serial crystallography or single-particle imaging experiments. Here, a new data-classification tool is reported that offers a variety of machine-learning algorithms to sort data trained either on manual data sorting by the user or by profile fitting the intensity distribution on the detector based on the experiment. This is integrated into an easy-to-use graphical user interface, specifically designed to support the detectors, file formats and software available at most X-ray free electron laser facilities. The highly modular design makes the tool easily expandable to comply with other X-ray sources and detectors, and the supervised learning approach enables even the novice user to sort data containing unwanted artefacts or perform routine data-analysis tasks such as hit finding during an experiment, without needing to write code.

Indexed as

data analysisexperimental artefactsgraphical user interfacesimage classificationmachine learningserial crystallographyX-ray diffraction patternsX-ray free electron lasers

Identifiers

PMID38596720
PMCPMC11001403
OpenAlexW4391740983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.