Evidence map›Paper›PMID 38596715›Full record

ArticleNeuro-oncology advances

The outcomes measured and reported in observational studies of incidental and untreated intracranial meningioma: A systematic review.

Christopher P Millward, Abdurrahman I Islim, Terri S Armstrong, Heather Barrington, Sabrina Bell, Andrew R Brodbelt, Helen Bulbeck, Linda Dirven, Paul L Grundy, Mohsen Javadpour and 19 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 15 institutions in 8 countries.

Christopher P MillwardInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0001-7727-1157
Abdurrahman I IslimInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.
Terri S ArmstrongNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-2414-0492
Heather BarringtonInstitute of Population Health, University of Liverpool, Liverpool, UK.
Sabrina BellThe Brain Tumour Charity, Hampshire, UK.
Andrew R BrodbeltInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.
Helen BulbeckBrainstrust - The Brain Cancer People, Isle of Wight, UK.
Linda DirvenDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0001-9157-9895
Paul L GrundyDepartment of Neurosurgery, University Hospital Southampton, Southampton, UK.
Mohsen JavadpourNational Centre for Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Sumirat M KeshwaraInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.
Shelli D KoszdinVeterans Affairs Healthcare System, Palo Alto, California, USA.
Anthony G MarsonInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.
Michael W McDermottDivision of Neuroscience, Florida International University, Miami, Florida, USA.
Torstein R MelingDepartment of Neurosurgery, Copenhagen University Hospital, Copenhagen, Denmark.
Kathy OliverInternational Brain Tumour Alliance, Tadworth, UK.
Puneet PlahaNuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
Matthias PreusserDivision of Oncology, Department of Medicine, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-3541-2315
Thomas SantariusDepartment of Neurosurgery, Addenbrooke's Hospital & University of Cambridge, Cambridge, UK.
Nisaharan SrikandarajahInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.
Martin J B TaphoornDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Carole TurnerDepartment of Neurosurgery, Addenbrooke's Hospital & University of Cambridge, Cambridge, UK.
Colin WattsInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Michael WellerDepartment of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-1748-174X
Paula R WilliamsonInstitute of Population Health, University of Liverpool, Liverpool, UK.
Gelareh ZadehDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-6637-4502
Amir H Zamanipoor NajafabadiDepartment of Ophthalmology, Leiden University Medical Centre, Haaglanden Medical Center, Haga Teaching Hospitals, Leiden and The Hague, The Netherlands.
Michael D JenkinsonInstitute of Systems, Molecular, & Integrative Biology, University of Liverpool, Liverpool, UK.
EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada
University of Liverpool · GBUniversity of Cambridge · GBBrain Tumour Charity · GBCopenhagen University Hospital · DKFlorida International University · USLeiden University Medical Center · NLUniversity of Toronto · CABeaumont Hospital · IELeiden University · NLMedical University of Vienna · ATNational Cancer Institute · USUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Birmingham · GBUniversity of Oxford · GBUniversity of Zurich · CH

Funding

Outcomes and Risk of Rare TumorsZIABC011837 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ARMSTRONG, TERRI S. · 2018 to 2024
$2.7M
6 · The paper itself

Abstract

Background: The clinical management of patients with incidental intracranial meningioma varies markedly and is often based on clinician choice and observational data. Heterogeneous outcome measurement has likely hampered knowledge progress by preventing comparative analysis of similar cohorts of patients. This systematic review aimed to summarize the outcomes measured and reported in observational studies. Methods: A systematic literature search was performed to identify published full texts describing active monitoring of adult cohorts with incidental and untreated intracranial meningioma (PubMed, EMBASE, MEDLINE, and CINAHL via EBSCO, completed January 24, 2022). Reported outcomes were extracted verbatim, along with an associated definition and method of measurement if provided. Verbatim outcomes were de-duplicated and the resulting unique outcomes were grouped under standardized outcome terms. These were classified using the taxonomy proposed by the "Core Outcome Measures in Effectiveness Trials" (COMET) initiative. Results: Thirty-three published articles and 1 ongoing study were included describing 32 unique studies: study designs were retrospective Conclusions: Outcome measurement across observational studies of incidental and untreated intracranial meningioma is heterogeneous. The standardized outcome terms identified will be prioritized through an eDelphi survey and consensus meeting of key stakeholders (including patients), in order to develop a Core Outcome Set for use in future observational studies.

Indexed as

COMETCore Outcome Setincidentalmeningiomaoutcomes

Identifiers

PMID38596715
PMCPMC11003528
OpenAlexW4392938398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.