Evidence map›Paper›PMID 38596707›Full record

ArticleOxford open neuroscience2022

Tissue-Wide Effects Override Cell-Intrinsic Gene Function in Radial Neuron Migration.

Andi H Hansen, Florian M Pauler, Michael Riedl, Carmen Streicher, Anna Heger, Susanne Laukoter, Christoph Sommer, Armel Nicolas, Björn Hof, Li Huei Tsai and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oxford open neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Andi H HansenInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Florian M PaulerInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Michael RiedlInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Carmen StreicherInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Anna HegerInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Susanne LaukoterInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Christoph SommerInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Armel NicolasInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Björn HofInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Li Huei TsaiPicower Institute for Learning and Memory, MIT, Cambridge, MA 02139, USA.
Thomas RülickeDepartment of Biomedical Sciences, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Simon HippenmeyerInstitute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Institute of Science and Technology Austria · ATUniversity of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian neocortex is composed of diverse neuronal and glial cell classes that broadly arrange in six distinct laminae. Cortical layers emerge during development and defects in the developmental programs that orchestrate cortical lamination are associated with neurodevelopmental diseases. The developmental principle of cortical layer formation depends on concerted radial projection neuron migration, from their birthplace to their final target position. Radial migration occurs in defined sequential steps, regulated by a large array of signaling pathways. However, based on genetic loss-of-function experiments, most studies have thus far focused on the role of cell-autonomous gene function. Yet, cortical neuron migration

Indexed as

4D live-imagingcell-autonomous gene functioncerebral cortex developmentmosaic analysis with double markers (MADM)neuronal migrationnon-cell-autonomous effectssingle-cell genetics

Identifiers

PMID38596707
PMCPMC10939316
OpenAlexW4284888933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.