Real-world Data of Leukopenia Evaluation as Seen in a Community Academic Center.

Suma S Chennapragada, Shivani Sharma, Neelakanta Dadi, Runhua Shi, Richard P Mansour

Open access · goldAbstract read

In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 76% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Suma S ChennapragadaDepartment of Hematology and Oncology, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.

Shivani SharmaDepartment of Internal Medicine, Louisiana State University Health Shreveport, 1541 Kings Highway, Shreveport, LA, 71103, USA.

Neelakanta DadiConway Regional Medical Center, Conway, AR, USA.

Runhua ShiDepartment of Hematology and Oncology, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.

Richard P MansourDepartment of Hematology and Oncology, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.

Louisiana State University · USRegional Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukopenia on routine laboratory testing creates a concerning situation for primary care providers due to its association with hematological malignancies. Although not all leukopenia is due to underlying cancer, it can trigger an expensive and exhausting work-up in the process of ruling it out. There is neither real-world data on the prevalent causes of leukopenia as seen in the community nor definitive guidelines on the utilization of flow-cytometry in this setting. We conducted this retrospective study at our community academic center to demonstrate the distribution of various causes of leukopenia as well as the utility of flow-cytometry. Our study demonstrates that benign reversible causes of leukopenia are most prevalent and flow-cytometry is useful only in some very specific settings. These results provide a real-world estimate for clinicians to make informed decisions while evaluating leukopenia.

Indexed as

Clinical utilityFlow-cytometryHematological malignanciesLeukopenia

Identifiers

PMID38596546

DOI10.55729/2000-9666.1273

PMCPMC11000836

OpenAlexW4388381818

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.