Evidence map›Paper›PMID 38596537›Full record

ArticleClinical parkinsonism & related disorders2024

Treatment of axial postural abnormalities in parkinsonism disorders: A systematic review of pharmacological, rehabilitative and surgical interventions.

Marialuisa Gandolfi, Christian Geroin, Gabriele Imbalzano, Serena Camozzi, Zoe Menaspà, Michele Tinazzi, Carlo Alberto Artusi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical parkinsonism & related disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06963918 (Effect of Expiratory Muscle Strength Training on Forward Trunk Flexion in Parkinson's Disease), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06963918 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Expiratory Muscle Strength Training on Forward Trunk Flexion in Parkinson's Disease

TypeinterventionalSponsorGeneral University Hospital, PragueRan2025 to 2026Enrolled30ConditionsParkinson DiseaseArmsExpiratory muscle strength training
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. What's in a name? reframing advanced Parkinson's disease as a multidimensional state.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in movement disorder therapeutics: A new era in neurology.Clinical parkinsonism & related disorders · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marialuisa GandolfiDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Christian GeroinDepartment of Surgery, Dentistry, Paediatric and Gynaecology, University of Verona, Italy.
Gabriele ImbalzanoDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
Serena CamozziDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Zoe MenaspàDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Michele TinazziDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Carlo Alberto ArtusiDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
University of Verona · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Axial postural abnormalities (PA) are frequent, highly disabling, and drug-refractory motor complications affecting patients with Parkinson's disease (PD) or atypical parkinsonism. Over the past few years, advances have been reached across diagnosis, assessment, and pathophysiological mechanisms of PA. Nonetheless, their management remains a challenge, and these disturbances are generally overlooked by healthcare professionals, potentially resulting in their worsening and impact on patients' disabilities. From shared consensus-based assessment and diagnostic criteria, PA calls for interdisciplinary management based on the complexity and multifactorial pathogenesis. In this context, we conducted a systematic literature review to analyze the available pharmacological and non-pharmacological treatment options for PA in PD according to the new expert-based classification of axial PA in Parkinsonism. Different multidisciplinary approaches, including dopaminergic therapy adjustment, physiotherapy, botulinum toxin injection, and deep brain stimulation, can improve PA depending on its type and severity. An early, interdisciplinary approach is recommended in PD patients to manage PA.

Indexed as

Axial Postural AbnormalitiesDeep brain stimulationDisabilityDrugPainParkinson diseaseRehabilitation

Identifiers

PMID38596537
PMCPMC11002662
OpenAlexW4392713646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.