Evidence map›Paper›PMID 38596485›Full record

ArticleWorld journal of gastroenterology2024

Serotonin receptor 2B induces visceral hyperalgesia in rat model and patients with diarrhea-predominant irritable bowel syndrome.

Zheng-Yang Li, Yu-Qing Mao, Qian Hua, Yong-Hong Sun, Hai-Yan Wang, Xuan-Guang Ye, Jing-Xian Hu, Ya-Jie Wang, Miao Jiang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zheng-Yang LiDepartment of Gastroenterology, Jinshan Hospital of Fudan University, Shanghai 201508, China.
Yu-Qing MaoDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Qian HuaDepartment of Gastroenterology, Jinshan Hospital of Fudan University, Shanghai 201508, China.
Yong-Hong SunDepartment of Gastroenterology, Dalian Friendship Hospital, Dalian 116001, Liaoning Province, China.
Hai-Yan WangDepartment of Gastroenterology, Jinshan Hospital of Fudan University, Shanghai 201508, China.
Xuan-Guang YeDepartment of Pathology, Jinshan Hospital of Fudan University, Shanghai 201508, China.
Jing-Xian HuDepartment of Gastroenterology, Jinshan Hospital of Fudan University, Shanghai 201508, China.
Ya-Jie WangDepartment of Gastroenterology, Jinshan Hospital of Fudan University, Shanghai 201508, China.
Miao JiangDepartment of Gastroenterology, Jinshan Hospital of Fudan University, Shanghai 201508, China. jiangmiao_@fudan.edu.cn.
Jinshan Hospital of Fudan University · CNShanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSerotonin receptor 2B (5-HT

aimTo investigate the possible involvement of 5-HT

methodsRectosigmoid biopsies were collected from 18 patients with IBS-D and 10 patients with irritable bowel syndrome with constipation who fulfilled the Rome IV criteria and 15 healthy controls. The expression level of the 5-HT

resultsHere, we observed greater expression of the 5-HT

conclusionOur finding that increased expression of the 5-HT

Indexed as

Irritable Bowel SyndromeAbdominal PainAcetatesAnimalsDiarrheaHumansHyperalgesiaRatsReceptor, Serotonin, 5-HT2BReceptors, SerotoninSerotoninAcetatesReceptor, Serotonin, 5-HT2BReceptors, SerotoninSerotoninAbdominal painDiarrhea-predominant irritable bowel syndromeSerotonin receptor 2BTransient receptor potential vanilloid type-1Visceral hypersensitivity

Identifiers

PMID38596485
PMCPMC11000090
OpenAlexW4392805961

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.